Shared features of pathogenetic aspects, autoimmunity and pharmacotherapy in coronavirus infection (COVID-19) and immunoinflammatory rheumatic diseases
Rutskaya-Moroshan S.S. Abisheva S.T. Lila A.M.
2022Ima-Press Publishing House
Sovremennaya Revmatologiya
2022#16Issue 582 - 87 pp.
The review is devoted to the relationship between the pathogenetic mechanisms of coronavirus infection (COVID-19) and immunoinflammatory rheumatic diseases (IRD). The current knowledge on the pathogenesis of COVID-19 is summarized, including the mechanisms of coagulopathy, hyperproduction of pro-inflammatory cytokines, and antiphospholipid antibodies that are common with IRD. The presence and clinical significance of detection of various autoantibodies in COVID-19, which probably play a pathogenetic role in immune dysregulation, were analyzed. Based on the data of recent studies, risk factors and features of the severe course of infection in patients with IRD are considered.
antirheumatic drugs , autoantibodies , COVID-19 , immunoinflammatory rheumatic diseases , risk factors
Text of the article Перейти на текст статьи
Astana Medical University, Nur-Sultan, 49A, Beibitshilik Street, Nur-Sultan, 010000, Kazakhstan
V.A. Nasonova Research Institute of Rheumatology, Moscow, 34A, Kashirskoe Shosse, Moscow, 115522, Russian Federation
Departmentof Rheumatology Russian Medical Academy of Continuing Professional Education, Moscow, 2/1, Barrikadnaya Street, Build. 1, Moscow, 125993, Russian Federation
Astana Medical University
V.A. Nasonova Research Institute of Rheumatology
Departmentof Rheumatology Russian Medical Academy of Continuing Professional Education
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026