Transition metals of arene derivatives with functionalized ionic liquid: DFT investigation, biological applications and electrochemical behavior of complexes
Rafikova K. Meriç N. Güzel R. Arslan N. Binbay N.E. Kayan C. Okumuş V. Zazybin A. Seilkhanov T. Binbay V. Aydemir M.
1 November 2022Elsevier B.V.
Inorganica Chimica Acta
2022#542
Mononuclear transition metal complexes based on ionic liquid have been prepared and characterized in detail. The biological properties of the three complexes were evaluated using radical scavenging activity, reducing power, antibacterial effect, DNA binding and cleavage activity. Among the complexes, [3-[(2R)-2-({[dichloro(η6-benzene)ruthenium]diphenylphosphanyl}oxy)-2-phenylethyl]-1-methyl-1H-imidazol-3-ium chloride] (4), demonstrated the highest radical scavenging (64.7 %) and reducing power activity (0.467) at 200 μg/ml concentration. The highest zone of inhibition was obtained from [3-[(2R)-2-({[dichloro(η6-p-cymene)ruthenium]diphenyl phosphanyl}oxy)-2-phenylethyl]-1-methyl-1H-imidazol-3-ium chloride] (3), against Bacillus cereus as 14 mm. Furthermore, all complexes were determined to have DNA binding and cleavage activities. Furthermore, theoretical DFT computations have also been carried out for the cationic complexes, to obtain minimum energy configuration of molecules. The effects of the chemical structures of three cationic complexes were also examined in relation to the variable property of electron-donating ligands for ruthenium-based complexes and iridium complex and their potential energy levels in ground and excited states HOMO and LUMO were determined.
Biological assays , DFT calculation , HOMO-LUMO , Ionic liquid , Iridium , Phosphinite , Ruthenium
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Institute of Geology and Oil and Gas Engineering Named After K. Turysov, Satbayev University, Kazakhstan
Kazakh-British Technical University, School of Chemical Engineering, Almaty, Kazakhstan
Dicle University, Faculty of Science, Department of Chemistry, Diyarbakir, 21280, Turkey
Dicle University, Technical Vocational School, Department of Hair Care and Beauty Services, Diyarbakir, 21280, Turkey
Department of Science, Faculty of Education, Dicle University, Diyarbakir, 21280, Turkey
Şırnak University, Faculty of Agriculture, Department of Field Crops, Şırnak, 73000, Turkey
Dicle University, Technical Vocational School, Department of Electronics, Diyarbakir, 21280, Turkey
Siirt University, Faculty of Science and Art, Department of Biology, Siirt, 56100, Turkey
Sh. Ualikhanov Kokshetau State University: Kokshetau, Kazakhstan
Dicle University, Institute of Natural Science, Department of Physics, Diyarbakir, 21280, Turkey
Institute of Geology and Oil and Gas Engineering Named After K. Turysov
Kazakh-British Technical University
Dicle University
Dicle University
Department of Science
Şırnak University
Dicle University
Siirt University
Sh. Ualikhanov Kokshetau State University: Kokshetau
Dicle University
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