Radiochemical aspects in modern radiopharmaceutical trends: a practical guide


Radchenko V. Baimukhanova A. Filosofov D.
2021Taylor and Francis Ltd.

Solvent Extraction and Ion Exchange
2021#39Issue 7714 - 744 pp.

Radiochemical separation and purification play an important role in the production and synthesis of radiopharmaceuticals in modern nuclear medicine. Several important criteria that need to be considered when choosing appropriate radiochemical separation methods are discussed in the present work. This review is designed to give an overview of important aspects of radiochemical separation for medical radionuclides and to bridge it with their production and chelation. Several important parameters, such as radionuclidic and radiochemical purity, specific activity are discussed. With this review, the authors would like to stress the importance of radiochemistry for radiopharmaceutical science, as it is very often underestimated.

nuclear medicine , radiochemical and radionuclidic purity , Radiochemical separation , radiopharmaceuticals , specific activity , targeted radionuclide imaging and therapy

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Life Sciences Division, TRIUMF, Vancouver, Canada
Department of Chemistry, University of British Columbia, Vancouver, BC, Canada
Dzelepov Laboratory of Nuclear Problems, Joint Institute for Nuclear Research, Dubna, Russian Federation
Scientific and Technical Center of Radiochemistry and Isotopes Production, Institute of Nuclear Physics, Almaty, Kazakhstan

Life Sciences Division
Department of Chemistry
Dzelepov Laboratory of Nuclear Problems
Scientific and Technical Center of Radiochemistry and Isotopes Production

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