Wessely immune rings following Keratorefractive Lenticule extraction: A case-based review


Pushkar S. Omirzak A. Remesnikov I.
June 2026Elsevier Inc.

American Journal of Ophthalmology Case Reports
2026#42

Purpose To describe two cases of immune-mediated corneal stromal infiltrates resembling Wessely immune rings following keratorefractive lenticule extraction (KLEx). Observations The first patient developed bilateral peripheral ring-shaped stromal infiltrates on postoperative day four, raising initial concern for infectious keratitis. Negative microbiologic work-up and favorable response to corticosteroids confirmed an immune-mediated etiology. The second patient presented with a unilateral peripheral stromal infiltrate on postoperative day one, which resolved with topical and subconjunctival corticosteroid therapy. In both cases, visual acuity improved to 20/20 without long-term sequelae. Conclusions and importance Wessely immune rings may develop after KLEx, mimicking infectious keratitis in the early postoperative period. Prompt recognition and differentiation of immune-mediated reactions from infections are essential to avoid unnecessary antimicrobial therapy and achieve favorable visual outcomes. Copyright



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Department of Ophthalmology, Astana Vision Clinic, Astana, Kazakhstan
Astana Vision Clinic, Astana, Kazakhstan

Department of Ophthalmology
Astana Vision Clinic

10 лет помогаем публиковать статьи Международный издатель

Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026