QBrainNet: harnessing enhanced quantum intelligence for advanced brain stroke prediction from medical imaging
Priyadharshini M. Murugesh V. Mahesh T.R. Albalawi E. Saidani O. Algarni A.
2025Frontiers Media SA
Frontiers in Medicine
2025#12
Introduction: Brain stroke is still one of the leading causes of death and long-term disability in the world. Early and correct diagnosis is therefore important for patient outcome. Although Convolution Neural Network (CNN), classical machine learning models, have achieved great progress in medical image classification, they have to face the performance saturation problem when dealing with high-dimensional and complex data such as medical images. To tackle these limitations, we propose QBrainNet, a quantum enhanced model, which is to enhance brain stroke prediction from medical imaging datasets. Methods: The model consists of Quantum Neural Networks (QNNs) applied as learning complex patterns in terms of medical images and Variational Quantum Circuits (VQCs) that will be used to optimize the classification. The feature extraction featured in the QNNs utilises quantum properties of superposition and entanglement to extract non-linear high-dimensional patterns in images related to stroke that may not be captured using classical limits. The VQCs, in turn, are applied to optimize the model performance, further allocating the boundaries of the decision and enhancing the model performance in terms of accuracy by optimizing the quantum gates and operators used during the work. QBrainNet utilizes the combination of such quantum properties as entanglement and superposition to represent more complicated non-linear patterns in stroke-specific images in a better manner than a classical application does. Results: This paper proposes a hybrid classical-quantum scheme: preprocessing classically, and learning quantum-enhanced. Quantum gates and operators are used when performing the quantum phase to optimize decision boundaries, achieving vastly enhanced prediction accuracy and efficiency performance. Experimental results indicate that QBrainNet has a better accuracy (96%) and AUC-PR (0.97) than the classical models like CNN, SVM, and Random Forest, proving the superior performance of QBrainNet in stroke detection. Discussion: The inference time is shorter, so the model can be used as a real-time clinical application. This article points to the possibilities quantum computing can have in revolutionizing medical diagnostics, especially stroke prediction. Copyright
brain stroke prediction , early stroke detection , medical imaging , quantum computing , quantum intelligence , quantum neural networks (QNN)
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Department of Computer Science & Engineering, Faculty of Science and Technology (IcfaiTech), ICFAI Foundation for Higher Education, Hyderabad, India
School of Computer Science, Coventry University Kazakhstan, Astana, Kazakhstan
Department of Computer Science and Engineering, Faculty of Engineering and Technology, JAIN (Deemed-to-be University), Bengaluru, India
Department of Computer Science, College of Computer Science and Information Technology, King Faisal University, Al Ahsa, Saudi Arabia
Department of Information Systems, College of Computer and Information Sciences, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia
Department of Informatics and Computer Systems, College of Computer Science, King Khalid University, Asir, Abha, Saudi Arabia
Center for Artificial Intelligence, King Khalid University, Asir, Abha, Saudi Arabia
Department of Computer Science & Engineering
School of Computer Science
Department of Computer Science and Engineering
Department of Computer Science
Department of Information Systems
Department of Informatics and Computer Systems
Center for Artificial Intelligence
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