Early predictor of bronchial suture failure after pneumonectomy

Ранний предиктор несостоятельности бронхиального шва после пневмонэктомии
Porkhanov V.A. Zhikharev V.A. Bushuev A.S. Zima V.S. Koryachkin V.A. Ivanova M.P.
2023 Media Sphera Publishing Group

Pirogov Russian Journal of Surgery
2023 Issue 10 71 - 77 pp.

Objective. To identify the relationship between serum CRP/albumin and bronchial suture failure after pneumonectomy. Material and methods. A retrospective analysis included 100 patients who underwent pneumonectomy with extended lymph node dissection for lung cancer. Patients were divided into 2 groups depending on postoperative complications: group 1 — bronchial stump failure, group 2 — no similar complications. In all patients, we analyzed markers of inflammation (C-reactive protein and albumin) in preoperative period and after 24 postoperative hours. Bronchial stump failure was found in 20 patients (10 patients (14.7%) after left-sided pneumonectomy and 10 (31%) patients after right-sided pneumonectomy). We found a significant relationship between serum CRP/albumin and bronchial stump failure after pneumonectomy (p<0.05). A prognostic formula was based on the ratio of serum C-reactive protein and albumin: PC = CRP/Alb, where PC — prognostic coefficient, CRP — serum C-reactive protein (mg/l) 24 hours after surgery, Alb — serum albumin (g/l) 24 hours after surgery. PC >2.6 determines high risk of bronchial stump failure after pneumonectomy, PC <2.6 — low risk. Sensitivity of this method is 90%, specificity — 97.5%.

albumin , bronchial suture failure , C-reactive protein , pneumonectomy

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Research Institution, Ochapovsky Regional Clinic Hospital No. 1, Krasnodar, Russian Federation
Kuban State Medical University, Krasnodar, Russian Federation
St. Petersburg State Pediatric Medical University, St. Petersburg, Russian Federation
Astana Medical University, Astana, Kazakhstan

Research Institution
Kuban State Medical University
St. Petersburg State Pediatric Medical University
Astana Medical University

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