Thromboembolic complications in urogenital cancers: incidence, risk factors and prevention
Распространенность тромбоэмболических осложнений при опухолях мочеполовой системы, факторы риска и профилактика
Popov S.V. Guseynov R.G. Isakova-Sivak I.N. Sivak K.V. Skryabin O.N. Perepelitsa V.V. Sengirbaev D.I. Bunenkov N.S. Osipov P.G. Lelyavina T.A.
2024ABV-press Publishing House
Onkourologiya
2024#20Issue 1164 - 173 pp.
Numerous studies indicate a decrease in overall survival among cancer patients who have developed thromboembolic complications. The article presents a review of literature on thromboembolic complications in patients with kidney, bladder, and prostate cancer. The analysis of publications indicates a variety of risk factors and heterogeneous frequency of thromboembolism in patients with malignant neoplasms of the genitourinary system. Prevention of thromboembolism is carried out at all stages of treatment: outpatient, after surgery, during chemotherapy, but is accompanied by a fairly high risk of hemorrhagic complications and recurrences. Direct oral anticoagulants are an alternative to low-molecular-weight heparin for prevention of cancer-associated thromboembolism due to their convenience, efficacy and safety for most patients. An important task is to select patients for primary thromboprophylaxis based on stratification of the risk of thromboembolic complications using prognostic scales.
bladder cancer , kidney cancer , morbidity , prevention , prostate cancer , risk factor , thromboembolism
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St. Luka’s Clinical Hospital, 46 Chugunnaya St., Saint Petersburg, 194044, Russian Federation
Saint Petersburg State University, 7–9 Universitetskaya Naberezhnaya, Saint Petersburg, 199034, Russian Federation
S.D. Asfendiyarov Kazakh National Medical University, 94 Tole bi St., Almaty, 050000, Kazakhstan
I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia, 6–8 L’va Tolstogo St., Saint Petersburg, 197022, Russian Federation
V.A. Almazov National Medical Research Centre, Ministry of Health of Russia, 2 Akkuratova St., Saint Petersburg, 197341, Russian Federation
Belgorod City Hospital No. 2, 46 Gubkina St., Belgorod, 308036, Russian Federation
St. Luka’s Clinical Hospital
Saint Petersburg State University
S.D. Asfendiyarov Kazakh National Medical University
I.P. Pavlov First Saint Petersburg State Medical University
V.A. Almazov National Medical Research Centre
Belgorod City Hospital No. 2
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