Extracorporeal membrane oxygenation: unmet needs and perspectives
Permenov B.A. Zimba O. Yessirkepov M. Anartayeva M. Suigenbayev D. Kocyigit B.F.
December 2024Springer Science and Business Media Deutschland GmbH
Rheumatology International
2024#44Issue 122745 - 2756 pp.
Extracorporeal Membrane Oxygenation (ECMO) has become an essential lifesaving intervention for individuals with severe cardiovascular and respiratory failure. Its application is expanding across several therapeutic contexts, surpassing conventional indications. The COVID-19 pandemic has significantly stressed worldwide health systems to manage acute respiratory failure. ECMO has been employed as a vital intervention, particularly for patients with severe COVID-19-induced acute respiratory distress syndrome (ARDS). ECMO is applicable throughout pregnancy. The principal indications for ECMO in pregnant women align with those in the general population. However, pregnancy complicates issues, necessitating consideration of both mother’s and infant’s well-being. Patients with systemic rheumatic diseases are prone to experience life-threatening complications. While a majority of these patients respond to immunosuppressive drugs, a small percentage suffer organ failure and may benefit from ECMO as a bridge to recovery. The article addresses coagulation therapies, highlighting the necessity of precise anticoagulation to avert both bleeding and thrombosis, particularly in patients requiring extended ECMO support. Additionally, the pharmacokinetics of antibiotics in ECMO patients are summarized, including the influence of the ECMO circuit on drug metabolism. Survey-based research offers valuable insights into ECMO use, procedures, and challenges. The paper evaluates current survey-based research and ECMO guidelines, highlighting clinical practice, training, and resource availability discrepancies across ECMO centers globally. Particular focus is placed on the rehabilitation requirements of ECMO survivors, acknowledging the importance of early mobilization and post-discharge care in improving long-term outcomes and quality of life.
COVID-19 , ECMO treatment , Extracorporeal membrane oxygenation , Practice guideline , Pregnancy , Rehabilitation , Rheumatic diseases , Surveys and questionnaires
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Department of Cardiac Surgery Anesthesiology and Intensive Care, Heart Center Shymkent, Shymkent, Kazakhstan
Department of Social Health Insurance and Public Health, South Kazakhstan Medical Academy, Shymkent, Kazakhstan
Department of Rheumatology, Immunology and Internal Medicine, University Hospital in Kraków, Kraków, Poland
National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland
Department of Internal Medicine N2, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine
Department of Biology and Biochemistry, South Kazakhstan Medical Academy, Shymkent, Kazakhstan
Heart Center Shymkent, Shymkent, Kazakhstan
Department of Physical Medicine and Rehabilitation, University of Health Sciences, Adana City Research and Training Hospital, Adana, Turkey
Department of Cardiac Surgery Anesthesiology and Intensive Care
Department of Social Health Insurance and Public Health
Department of Rheumatology
National Institute of Geriatrics
Department of Internal Medicine N2
Department of Biology and Biochemistry
Heart Center Shymkent
Department of Physical Medicine and Rehabilitation
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