Neuroprotective effects of magnesium: implications for neuroinflammation and cognitive decline
Patel V. Akimbekov N.S. Grant W.B. Dean C. Fang X. Razzaque M.S.
2024Frontiers Media SA
Frontiers in Endocrinology
2024#15
Neurodegenerative diseases, which are characterized by progressive neuronal loss and cognitive decline, are a significant concern for the aging population. Neuroinflammation, a shared characteristic of these diseases, is implicated in their pathogenesis. This article briefly summarizes the role of magnesium, an essential mineral involved in numerous enzymatic reactions and critical for neuronal bioactivity, in the context of neuroinflammation and cognitive decline. The potential neuroprotective effects of magnesium, including the mechanisms of neuroprotection by magnesium through maintaining neuronal ion homeostasis, reducing inflammation, and preventing excitotoxicity, are also described. Additionally, we discuss the impact of inadequate magnesium on neuroinflammation and its potential as a therapeutic agent for attenuating cognitive decline to improve neurodegenerative conditions. Copyright
cognitive decline , magnesium , neurodegenerative disease , neuroinflammation , neuroprotection
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Department of Pathology, Lake Erie College of Osteopathic Medicine, Erie, PA, United States
Scientific-Practical Center, West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan
Sustainability of Ecology and Bioresources, Al-Farabi Kazakh National University, Almaty, Kazakhstan
Sunlight, Nutrition, and Health Research Center, San Francisco, CA, United States
New Capstone, Inc., Mooresville, NC, United States
Department of Neuroscience, School of Medicine, University of Texas Rio Grande Valley (UTRGV), Edinburg, TX, United States
Department of Medical Education, School of Medicine, University of Texas Rio Grande Valley (UTRGV), Edinburg, TX, United States
Department of Pathology
Scientific-Practical Center
Sustainability of Ecology and Bioresources
Sunlight
New Capstone
Department of Neuroscience
Department of Medical Education
10 лет помогаем публиковать статьи Международный издатель
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