Interplay of photobiological stress and chronodermal dysfunction: two-dimensional nanomaterial strategies for barrier restoration in smart cosmetics
Pan X. Zhao Y. Huang W. Wu J. Liang J. Xie Y. Chen Y. Zhao W.
December 2025Springer Nature
Archives of Dermatological Research
2025#317Issue 1
The increasing prevalence of nighttime electronic device usage has raised concerns about blue light exposure as a significant factor contributing to skin barrier damage. To address the limitations of current protective strategies—such as low transdermal efficiency of antioxidants and inadequate circadian regulation—this study proposes an intelligent skincare system utilizing two-dimensional nanomaterials. The developed approach integrates MXene and transition metal dichalcogenides for enhanced blue light shielding, antioxidant delivery, and microbiome regulation. Key innovations include a responsive release mechanism tailored to skin conditions and a day-night differentiated repair mode. This work establishes a comprehensive strategy combining electromagnetic protection, circadian rhythm synchronization, and barrier recovery, providing a foundation for future bioelectronic skincare technologies.
Blue light exposure , Circadian rhythm disorder , Intelligent responsive cosmetics , Two-dimensional nanomaterials
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Zhongshan Advanced New Functional Materials Engineering Technology Research Center, Zhongshan Polytechnic, Zhongshan, 528400, China
Laboratory of Functional Nanomaterials, Institute of Combustion Problems, Al-Farabi Kazakh National University, Bogenbay Batyr Str. 1721, Almaty, 050012, Kazakhstan
Faculty of Chemistry and Chemical Technology, Al-Farabi Kazakh National University, 71 al-Farabi Ave., Almaty, 050040, Kazakhstan
Faculty of Chemical Technology, Poznan University of Technology, Berdychowo 4, Poznan, 60965, Poland
School of Energy Science and Technology, Henan University, Kaifeng, 475004, China
Zhongshan Advanced New Functional Materials Engineering Technology Research Center
Laboratory of Functional Nanomaterials
Faculty of Chemistry and Chemical Technology
Faculty of Chemical Technology
School of Energy Science and Technology
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