GC/MS chemical profiling and isolation of secondary metabolites from Leontice ewersmannii
Omirzakova N. Samy M.N. Kiyekbayeva L. Datkhayev U. Akhtayeva N. Ross S.A.
2025Taylor and Francis Ltd.
Natural Product Research
2025#39Issue 144171 - 4175 pp.
GC/MS chemical profiling of the aerial parts of Leontice ewersmannii revealed the presence of various bioactive compounds of which 20 compounds were in n-hexane fraction and 3 compounds in basic DCM fraction. Among the identified compounds alkaloids, fatty acids and their esters, fatty alcohols, hydrocarbons, and sterol were detected. Phytochemical investigation of the aerial parts of L. ewersmannii led to isolation of 17 compounds including 1-heptacosanol (1), phytol (2), lupenone (3), palmitic acid (4), oleic acid (5), stigmasterol (6), stigmast-7-en-3-ol (7), methyl palmitate (8), methyl linoleate (9), butyl palmitate (10), butyl linoleate (11), dimethyl dodecanedioate (12), methyl cerebronate (13), β-sitosterol (14), β-sitosterol 3-O-β-glucopyranoside (15), sophoridine (16) and camoensine (17). The structures of the isolated compounds were determined by 1D NMR, HR-ESI-MS, and GC-MS. All methyl esters of fatty acids are possible artifacts during extraction. Additionally, the antimicrobial activity of the total extract and different fractions was screened, and they exhibited no inhibition of the growth at the tested concentration ranging from 8 to 200 μg/mL.
alkaloids , fatty acids , fatty alcohols , Leontice ewersmannii , sterols
Text of the article Перейти на текст статьи
National Center for Natural Products Research, School of Pharmacy, University of MS, University, MS, United States
Department of Pharmacy, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan
Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, Egypt
Department of Biology and Biotechnology, Al-Farabi Kazakh National University, Almaty, Kazakhstan
Department of BioMolecular Science, Division of Phamacognosy, School of Pharmacy, University of Mississippi, University, MS, United States
National Center for Natural Products Research
Department of Pharmacy
Department of Pharmacognosy
Department of Biology and Biotechnology
Department of BioMolecular Science
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026