The Evolving Role of Palliative Care in Older People with Glioblastoma
Okon I.I. Osama M. Akpan A. Fabrini Paleare L.F. Ferreira M.Y. Shafqat M.D. Razouqi Y. James E. Omer M. Jaafar I.K. Chaurasia B. Iqbal M. Balogun S. Maidan A. Hussain Jakhar M.O. Precious F.K. Gbayisomore T.J. Lucero-Prisno D.E., III
December 2024Elsevier Inc.
World Neurosurgery
2024#192140 - 149 pp.
Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor in older adults and has a poor prognosis and limited response to treatment. The growing impact of palliative care on older people undergoing neurosurgery is becoming increasingly important. Palliative care aims to improve the quality of life for people and their families by addressing their physical, psychosocial, and spiritual needs. The prevalence of GBM peaks between 65 and 84 years of age, and treatment options may be hindered by chronic multiple conditions in older people. Older people are at risk of receiving suboptimal end-of-life care due to factors such as a focus on curative medicine, acceptance of terminal illness, which may discourage the person, and lack of awareness of palliative care for people with a noncancer diagnosis. People with GBM experience a significant illness burden, including neurological symptoms, mood disturbances, and cognitive impairment. A multidisciplinary approach, including palliative care, is recommended to improve treatment outcomes and quality of life. However, palliative care is often not consistently included in multidisciplinary teams despite the lack of curative treatment options and significant symptom burden. The palliative care needs of people with GBM can be complex, and published evidence in this area is limited. Nonetheless, there are similarities between the needs of people with GBM and those with other, more common cancer diagnoses and nonmalignant chronic neurologic illnesses. The integration of palliative care into the management of older people with GBM during neurosurgery is crucial for addressing their unique needs and improving their quality of life. In this review, we aimed to comprehensively evaluate the impact of palliative care on people with GBM and its importance.
Glioblastoma , Neurosurgery , Older people , Palliative care
Text of the article Перейти на текст статьи
Department of Neurosurgery, Dell Medical School, University of Texas, Austin, TX, United States
Department of Neurosurgery, Nasser Institute for Research and Treatment, Cairo, Egypt
Consultant Geriatrician, Bunbury Regional Hospital, Banbury, WA, Australia
Department of Medicine, Pontifical Catholic University of Paraná, PR, Curitiba, Brazil
Department of Neurosurgery, Lenox Hill, Hospital/Northwell Health, New York, NY, United States
Clinical Health Science, Shifa College of Medicine, Islamabad Capital Territory, Islamabad, Pakistan
Interdisciplinary Laboratory of Biotechnology and Health, Neurosciences and Cellular Physiology research team, Mohammed VI University of Sciences and Health (UM6SS), Casablanca, Morocco
Department of Medicine and surgery, University of Benin, Edo State, Nigeria
Department of Surgery, International School of Medicine-International University of Kyrgyzstan, Bishkek, Bishkek City, Kyrgyzstan
Department of Public Health, University of Warwick, Coventry, United Kingdom
Department of Neurosurgery, Neurosurgery Clinic, Birgunj, Nepal
Department of Neurosurgery, Obafemi Awolowo University Teaching Hospitals Complex, Osun State, Ile-Ife, Nigeria
Department of Neurosurgery, National Center for Neurosurgery, Astana, Kazakhstan
Department of Medicine, King Edward Medical University, Lahore, Pakistan
College of Medicine, University of Nigeria, Enugu State, Nigeria
Department of Anatomy, University of Medical Sciences, Ondo State, Nigeria
Department of Global Health and Development, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom
Office for Research, Innovation and Extension Services, Southern Leyte State University, Southern Leyte, Sogod, Philippines
Center for University Research, University of Makati, Makati City, Philippines
Department of Neurosurgery
Department of Neurosurgery
Consultant Geriatrician
Department of Medicine
Department of Neurosurgery
Clinical Health Science
Interdisciplinary Laboratory of Biotechnology and Health
Department of Medicine and surgery
Department of Surgery
Department of Public Health
Department of Neurosurgery
Department of Neurosurgery
Department of Neurosurgery
Department of Medicine
College of Medicine
Department of Anatomy
Department of Global Health and Development
Office for Research
Center for University Research
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026