TOXOPLASMOSIS INFECTION IN AN HIV-NEGATIVE PATIENT PRESENTING WITH CLINICAL AND MRI FINDINGS SIMILAR TO THOSE OF MULTIPLE SCLEROSIS
Nurgaliyeva B. Nyssanbayeva K. Choudhary M.
2024SMC Media Srl
European Journal of Case Reports in Internal Medicine
2024#11Issue 11
Toxoplasmosis is a parasitic infection that can present in various clinical forms, ranging from asymptomatic to severe neurological manifestations. The primary sources of infection include undercooked meat, unwashed produce and contact with cat faeces. Toxoplasmosis can lead to encephalitis, particularly in immunocompromised patients, and is often misdiagnosed as other neurological conditions such as multiple sclerosis (MS). We report the case of a 44-year-old male from Almaty, Kazakhstan, who presented with neurological symptoms including headaches, dizziness, diplopia, leg weakness and elevated blood pressure. The patient had a history of consuming undercooked meat, but no prior neurological conditions. Initial magnetic resonance imaging (MRI) revealed demyelinating lesions, leading to a diagnosis of MS. However, high levels of IgG antibodies against Toxoplasma gondii were detected, prompting further testing. A polymerase chain reaction test for toxoplasmosis was negative, but the patient was treated empirically with trimethoprim and sulfamethoxazole for six months. A follow-up MRI showed a significant reduction in brain lesions, and the patient’s symptoms improved.
central nervous system , MRI , Toxoplasmosis
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Department of Propaedeutic of Internal Diseases, Kazakh National Medical University, Almaty, Kazakhstan
Jeevan Clinic, Gurgaon, India
Department of Propaedeutic of Internal Diseases
Jeevan Clinic
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