Acute pancreatitis as a rare adverse event following COVID-19 vector-based vaccination: A case report
Nurgaliyeva B. Moldakaryzova A. Khaidarov S. Aldasheva Z.
15 December 2025Mattioli 1885
Acta Biomedica
2025#96Issue 6
Background: Acute pancreatitis (AP) has been reported rarely after vaccination against SARS-CoV-2. Case: We describe a 41-year-old vegetarian, non-smoking male who developed AP five days after the first dose of the adenoviral vector vaccine Gam-COVID-Vac (Sputnik V). On admission serum amylase was 3600 U/L and abdominal ultrasound demonstrated an enlarged, oedematous pancreas without gallstones. The patient responded to conservative therapy and was discharged after seven days. Conclusion: Although causal inference cannot be drawn from a single observation, clinicians should remain aware of AP as a potential event after vector-based COVID-19 vaccination.
acute pancreatitis , adverse event , case report , COVID-19 , vector vaccine
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Department of propaedeutic of internal diseases, Kazakh National Medical University named after S. Asfendyarov, Almaty, Kazakhstan
KazMed Company LLP Outpatient Clinic, Almaty, Kazakhstan
Department of Molecular Biology and Medical Genetics, Kazakh National Medical University named after S. Asfendyarov, Almaty, Kazakhstan
Kazakhstan Medical University “Kazakhstan School of Public Health”, Almaty, Kazakhstan
Department of propaedeutic of internal diseases
KazMed Company LLP Outpatient Clinic
Department of Molecular Biology and Medical Genetics
Kazakhstan Medical University “Kazakhstan School of Public Health”
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