Association between body mass index and patient-reported-outcome questionnaire scores (CAT™, ACT™, mMRC dyspnoea scale, IPAQ) in Ukraine, Kazakhstan and Azerbaijan: results of the CORE study

Nugmanova D. Feshchenko Y. Iashyna L. Polianska M. Malynovska K. Stafeyeva I. Makarova J. Vasylyev A.
December 2021 BioMed Central Ltd

BMC Pulmonary Medicine
2021 #21 Issue 1

Background: The overweight/obese population (evaluated by a body mass index, BMI) represents a global health problem and contributes to the development of various chronic diseases. In this epidemiological study we evaluated this relationship by analyzing patient-reported questionnaires related to respiratory function, physical activity and BMI. Methods: In 2013–2015, adult residents of selected cities were enrolled to this study in: Ukraine (M/F: 403/561), Kazakhstan (M/F = 348/597) and Azerbaijan (M/F: 389/544). Height was measured using a vertical measuring board, and body weight was measured by using portable digital scales. All participants were interviewed using CAT™, mMRC scale and IPAQ; respondents who also reported wheezing or whistling chest sounds during the previous 12 months additionally ACT™. Results: 45.4% of respondents in Ukraine, 47.6% in Kazakhstan and 54.9% of respondents in Azerbaijan were found to be overweight/obese (BMI ≥ 25 kg/m²). The mean CAT™ total score among this population versus those respondents with a normal weight was 5.2 versus 3.6 (Ukraine, p < 0.001), 4.2 versus 2.9 (Kazakhstan, p < 0.001) and 5.9 versus 4.3 (Azerbaijan, p < 0.001). The number of respondents without airflow limitations (mMRC score 0) among overweight/obese respondents versus normal weight respondents was 298 (68.2%) versus 456 (86.7%) in Ukraine, 261 (58.1%) versus 387 (78.2%) in Kazakhstan and 343 (67.1%) versus 345 (82.3%) in Azerbaijan. The ACT™ total score between overweight/obese respondents and normal weight respondents was not statistically different. IPAQ showed a tendency towards a higher proportion of “low activity” results (compared to “moderate” and “high”) in the overweight/obese subgroup (24.7% vs. 23.8% in Kazakhstan, 18.5% vs. 14.6% in Azerbaijan), and in Ukraine this difference was significant (12.4% vs. 5.2%, p < 0.001). Conclusion: CAT™ and mMRC are widely used tools for respiratory function assessment. Despite CAT™ scores being close to a normal value (< 5), the relationship of both CAT™ and mMRC scores with being overweight/obese was demonstrated in the general adult population of three CIS countries. IPAQ may also be a useful instrument for measuring activity level however, more objective studies are required to evaluate the relationship between BMI and physical activity.

Asthma control test™ , Azerbaijan , Body mass index , COPD assessment test™ , International physical activity questionnaire , Kazakhstan , Modified medical research council dyspnoea , Ukraine

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Semey State Medical University, Almaty, Kazakhstan
National Institute of Phtysiology and Pulmonology Named After F.G. Yanovskiy NA, Kyiv, Ukraine
GlaxoSmithKline, Kiev, Ukraine
GlaxoSmithKline, Moscow, 125167, Russian Federation
GlaxoSmithKline, Dubai, United Arab Emirates

Semey State Medical University
National Institute of Phtysiology and Pulmonology Named After F.G. Yanovskiy NA
GlaxoSmithKline
GlaxoSmithKline
GlaxoSmithKline

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