Immune Boosters and Immunotherapy in Allergic Diseases and in Cancer Management
Naqvi M.R. Abbas S. Abbas M. Batool A. Mansoor G. Bashir S. Naeem M.Y. Selamoglu Z.
2025Razi Vaccine and Serum Research Institute
Archives of Razi Institute
2025#80Issue 1371 - 374 pp.
Allergy and cancer are immune-mediated diseases that present substantial clinical challenges, and immunotherapy, which exploits the immune system for therapeutic intervention, holds immense potential in their management. This review scrutinises the immunotherapeutic landscape of allergic diseases and cancer, emphasising their shared immunological underpinnings and therapeutic implications. Allergy manifests as exaggerated immune responses to innocuous antigens, culminating in inflammation and tissue damage. The therapeutic objective in the context of allergy is to induce immune tolerance to allergens, thereby alleviating symptoms and improving disease outcomes. Conversely, cancer employs multifaceted immune evasion mechanisms to evade immunosurveillance and propagate malignancy. Immunotherapeutic strategies in cancer endeavour to reinvigorate antitumor immunity and eradicate neoplastic cells. A notable development in this field is the emergence of immune checkpoint inhibitors as a cornerstone in cancer immunotherapy, unleashing the immune systems potential to recognise and eliminate malignant cells. This review elucidates the intricate immunological mechanisms underlying allergy and cancer pathogenesis and delineates the diverse immunotherapeutic strategies employed in each context. It underscores the convergence of immunological principles and clinical applications in shaping the therapeutic landscape of allergic diseases and cancer. By synthesising fundamental immunology with clinical insights, immunotherapy offers transformative prospects for personalised medicine, as evidenced by recent advancements, including immune checkpoint blockade and adoptive cell therapy, which have revolutionized the treatment paradigm in cancer.
Allergy , Cancer , Immune Boosters , Immunotherapy
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Medical Director and Cancer Liason Physician Intermountain Health Care, Denver, United States
Allergy and Asthma Center, Blue Area, Islamabad, Pakistan
Clinical and Tropical Diseases Research Division, National Institute of Health, Islamabad. Former HOD Allergy and Immunology, NIH, Islamabad, Pakistan
Allergy and Asthma Center, Islamabad, Pakistan
Pak Emirates Military Hospital, Pakistan
Department of Plant Production and Technologies, Faculty of Agricultural Sciences and Technologies, Nigde Omer Halisdemir University, Nigde, Turkey
Department of Medical Biology, Medicine Faculty, Nigde Omer Halisdemir University, Nigde, Turkey
Western Caspian University, Baku, Azerbaijan
Khoja Akhmet Yassawi International Kazakh-Turkish University, Faculty of Sciences, Department of Biology, Central Campus, Turkestan, Kazakhstan
Medical Director and Cancer Liason Physician Intermountain Health Care
Allergy and Asthma Center
Clinical and Tropical Diseases Research Division
Allergy and Asthma Center
Pak Emirates Military Hospital
Department of Plant Production and Technologies
Department of Medical Biology
Western Caspian University
Khoja Akhmet Yassawi International Kazakh-Turkish University
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026