Results of minimally invasive treatment of liver echinococcosis in comparison with traditional surgical methods

Результаты мини-инвазивного лечения (PAIR) при эхинококкозе печени в сравнении с традиционными хирургическими методами
Nagasbekov M.S. Baimakhanov Z.B. Kaniyev S.A. Nurlanbayev E.K. Chormanov A.Ch. Baimakhanov B.B.
2021 VIDAR Publishing House

Annals of HPB Surgery
2021 #26 Issue 4 61 - 68 pp.

Aim. To analyze the effectiveness of PAIR in comparison with traditional surgical methods. Materials and methods. A retrospective analysis of 199 patients who underwent surgical treatment of hepatic echinococcosis was carried out. Pericystectomy was performed on 95 (47.7%) patients (1st group), traditional echinococcectomy - 55 (27.6%; 2nd group), PAIR - 49 (24.6%; 3rd group). All patients received antihelmintic therapy for 2 months in the postoperative period. Results. Patients of the group 3 had significantly more CE1 cysts compared with the groups 2 and 1 - 38 (77.5%) versus 19 (34.5%) and 44 (46.3%; p < 0.05) respectively. In group 2, CE2 and CE3 cysts were predominant. The duration of the operation in group 3 was significantly shorter than in group 1 and 2 - 58.2 (25-170), 194.8 (85-440) and 217 (75-540) minutes (p < 0.05). In group 1, intraoperative blood loss was higher than in group 2 - 165.4 ml (10-1000) and 106.7 ml (10-500; p < 0.05). There were no statistically significant differences between the groups in postoperative complications according to Clavien-Dindo. The duration of postoperational hospital stay of patients from the group 3 was shorter than for 1 and 2 groups - 4.3 (2-11) days, 8.03 (5-16) days and 8.08 (4-20) days (p < 0.05) respectively. There was no disease recurrence during the follow-up period. Conclusion. The optimal treatment should be based on the stage of the disease. In CE1, the most effective method is PAIR, which is characterized by a shorter postoperational hospital stay and early recovery. In multivesicular cysts (CE2-CE3b), traditional methods of treatment are effective.

Albendazole , Antihelmintic therapy , Echinococcectomy , Echinococcosis , Liver , PAIR , Pericystectomy

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A.N. Syzganov National Scientific Center for Surgery, JSC, 62, str. Zheltoksan, Almaty, 050004, Kazakhstan
“Asfendiyarov Kazakh National Medical University”, NC JSC, 94, str. Tole bi, Almaty, 050012, Kazakhstan

A.N. Syzganov National Scientific Center for Surgery
“Asfendiyarov Kazakh National Medical University”

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