COMPARATIVE STUDY OF ANTIBACTERIAL EFFECTS OF MODIFIED PREPARATIONS CONTAINING METAL NANOPARTICLES
Myrzakozha D. Issabekova T. Rakhymbayev N. Karlova E. Nechepurenko E.
2025Georgian Association of Business Press
Georgian Medical News
2025#363Issue 6150 - 157 pp.
The study evaluated the inhibitory effects of pharmaceutical formulations enriched with metal-based nanoparticles on Staphylococcus aureus, Escherichia coli, and Salmonella dublin. Transmission electron microscopy revealed agglomerated chain-like structures of nanoparticles measuring 36–122 nm. Most metal components, including cobalt, zinc, manganese, and germanium, significantly reduced bacterial viability, whereas magnesium showed no suppressive effect. Bactericidal efficacy was confirmed both by diffusion assays and morphological disruption observed under high-resolution microscopy. The outcomes suggest the selective potency of certain metal nanoparticles against nosocomial bacteria and support their further consideration in the development of antimicrobial agents.
bactericidal effect. , disk diffusion method , Nanoparticles , pathogenic microorganisms and opportunistic pathogens
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Department of Pharmacy, Asfendiyarov Kazakh National Medical University, Tole Bi 94, Almaty, Kazakhstan
Department of Pharmacy
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026