Foam-Based Drug Delivery Systems for Skin Disorders: A Comprehensive Review


Myrzagulova S. N Z.A. Kumar M. Kumar D. Kumar A.
May 2025Springer Science and Business Media Deutschland GmbH

AAPS PharmSciTech
2025#26Issue 4

Foam-based drug delivery systems signify a significant innovation in dermatology, facilitating improved drug penetration and administration via a gas-liquid dispersion matrix. These formulations have shown considerable promise in the medical, cosmetic, and pharmaceutical fields. Recent improvements in topical foams have resulted in their extensive utilization in dermatological therapies, with a growing emphasis on categorization techniques grounded in formulation composition and the creation of novel methodologies for assessing essential physicochemical factors. Foam formulations comprising calcipotriol and betamethasone demonstrate 30% enhanced therapeutic effectiveness in the treatment of psoriasis compared to traditional topical therapies. The low-density, aerated structure of foams promotes improved skin covering and hydration, which is especially advantageous for disorders like eczema. Moreover, novel advances such as propellant-free foams and the incorporation of nanotechnology have broadened the use of foam-based delivery methods in targeted drug administration and customized medicine. Ongoing research into new biomaterials and refined formulation procedures seeks to overcome these constraints, ensuring that foam-based systems emerge as a breakthrough method in dermatological care. These systems promise to enhance clinical results and overall patient quality of life by increasing medication bioavailability, patient adherence, and therapeutic effectiveness.

acne , eczema , foam-based delivery system , fungal infections , psoriasis , wound healing

Text of the article Перейти на текст статьи

Department of Pathological Physiology, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan
Department of Pathological Physiology, West Kazakhstan Marat, Ospanov Medical University, Aktobe, Kazakhstan
Department of Pharmaceutical Sciences & Technology, Maharaja Ranjit Singh Punjab Technical University (MRSPTU), 151001, Punjab, Bathinda, India
Institute of Pharmaceutical Research, GLA University, Uttar Pradesh, Mathura, 281406, India

Department of Pathological Physiology
Department of Pathological Physiology
Department of Pharmaceutical Sciences & Technology
Institute of Pharmaceutical Research

10 лет помогаем публиковать статьи Международный издатель

Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026