ASSESSMENT OF RISK FACTORS FOR ADVERSE CARDIOVASCULAR AND RENAL COMPLICATIONS IN TYPE 2 DIABETES MELLITUS IN ELDERLY AND OLD AGE

Murkamilov I.T. Aitbaev K.A. Murkamilova Z.A. Fomin V.V. Yusupov F.A. Yusupova T.F. Yusupova Z.F. Satkynalieva Z.T. Tologonov B.T. Gassanov K.A.
2023 Klinichescheskaya Laboratornaya Diagnostika

Klinichescheskaya Laboratornaya Diagnostika
2023 #68 Issue 6 323 - 332 pp.

Frequency of risk factors for adverse cardiovascular and renal complications in type 2 diabetes mellitus (DM 2) in elderly (n=70) and old age (n=19) was studied. Elderly patients often had chronic coronary syndrome (CCS, 67.1%), arterial hypertension (AH, 65.7%) and obesity (45.7%). Common variants of heart damage were left ventricular (LV) hypertrophy (51.4%) and LV diastolic dysfunction (70%). Disturbances in lipid metabolism were represented mainly by dyslipidemia (32.8%). Hypercholesterolemia (HC) was significantly more common in women, while fasting hyperglycemia and elevated levels of cystatin C were found in men. Persons of old age were more likely to be overweight (68.40%) and have AH (52.60%). Women were significantly more likely to be overweight and have AH, CCS, chronic heart failure with low ejection fraction, carotid atherosclerosis (CA), LV diastolic dysfunction and left atrial enlargement (LAE). The most common types of disorder of the cardiovascular system were LAE (84.1%), LV diastolic dysfunction (57.8%) and CA (57.8%). Lipid metabolism disorder was represented by HC (42.1%). Atherogenic dyslipidemia and fasting glycemia were significantly more common in women, while hyperphosphatemia – in men. In elderly patients, the value of the LV mass index was significantly influenced by the concentration of cystatin C, the value of glomerular filtration and proteinuria, while in old patients – by the content of phosphorus in blood. The value of the filtration function of the kidneys in elderly patients was influenced by the level of systolic blood pressure and concentration of total cholesterol.

diabetes mellitus , elderly and old patient , glomerular filtration rate , glycohemoglobin , heart failure , myocardium , phosphorus , renal failure

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Kyrgyz State Medical Academy named after I.K. Akhunbaev, Bishkek, 720020, Kyrgyzstan
Kyrgyz-Russian Slavic University named after the First President of the Russian Federation B.N. Yeltsin, Bishkek, 720000, Kyrgyzstan
Scientific Research Institute of Molecular Biology and Medicine at the National Center of Cardiology and Therapy named after аcademician Mirsaid Mirrakhimov under the Ministry of Health of the Kyrgyz Republic, Bishkek, 720040, Kyrgyzstan
FSAEI HE First Moscow State Medical University named after I.M. Sechenov, Moscow, 119991, Russian Federation
Osh State University, Osh, 723500, Kyrgyzstan
National Hospital under the Ministry of Health of the Kyrgyz Republic, Bishkek, 720040, Kyrgyzstan
South Kazakhstan Medical Academy, Shymkent, 160019, Kazakhstan

Kyrgyz State Medical Academy named after I.K. Akhunbaev
Kyrgyz-Russian Slavic University named after the First President of the Russian Federation B.N. Yeltsin
Scientific Research Institute of Molecular Biology and Medicine at the National Center of Cardiology and Therapy named after аcademician Mirsaid Mirrakhimov under the Ministry of Health of the Kyrgyz Republic
FSAEI HE First Moscow State Medical University named after I.M. Sechenov
Osh State University
National Hospital under the Ministry of Health of the Kyrgyz Republic
South Kazakhstan Medical Academy

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