Awake magic: glioblastoma resection under 5-aminolevulinic acid guidance during awake craniotomy. A case report with video demonstration


Moldabekov A. Maidan A. Ryskeldiyev N. Ashirov N. Akshulakov S.
2024National Scientific Medical Center

Journal of Clinical Medicine of Kazakhstan
2024#21Issue 193 - 96 pp.

An awake craniotomys primary goal is to remove the tumor or damaged cells as much as possible without affecting the patients capacity for clear thought or other crucial functions. This surgical procedure offers a better prognosis by balancing the maximum removal of lesions with the preservation of working zones. For patients with malignant gliomas, the current neurosurgical objective is to resection the large part of a tumor using contrast and not causing neurological deficits. Neurooncological patients are required to have further chemotherapy and radiotherapy, with a control MRI of the brain in 3 and 6 months. Real multidisciplinary work should be provided to improve each patients quality of life and overall survival. This paper aims to report a single case of successful awake craniotomy with fluorescence guidance and discuss the outcomes of the performed surgery.

5-aminolevulinic acid , awake craniotomy , gliolan

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Department of Brain Neurosurgery, National Centre for Neurosurgery, Astana, Kazakhstan
Department of Minimal Invasive Neurosurgery, National Centre for Neurosurgery, Astana, Kazakhstan

Department of Brain Neurosurgery
Department of Minimal Invasive Neurosurgery

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