Ecological risk assessment and long-term environmental pollution caused by obsolete undisposed organochlorine pesticides
Mit N. Cherednichenko O. Mussayeva A. Khamdiyeva O. Amirgalieva A. Begmanova M. Tolebaeva A. Koishekenova G. Zaypanova S. Pilyugina A. Amandykova M. Tlenshieva A. Nurzhanova A. Mamirova A. Bekmanov B. Djansugurova L.
2021Bellwether Publishing, Ltd.
Journal of Environmental Science and Health - Part B Pesticides, Food Contaminants, and Agricultural Wastes
2021#56Issue 5490 - 502 pp.
Obsolete organochlorine pesticides (OSPs) are currently prohibited as persistent organic pollutants that contaminate the environment. If undisposed, they continue to pollute soil and water, to accumulate in the food chain and to harm plants, animals and the human body. The aim of the study was to assess water and soil pollution around the storehouses of undisposed, banned OSPs and their possible genotoxic effect. The storehouses in four villages near Almaty, Kazakhstan were investigated. Chemical analysis confirmed contamination of water and soil around storehouses with OSPs. The genotoxic effect of water and soil samples was evaluated using model objects: S.typhymurium, D.melanogaster, sheep lymphocytes cultures and human lymphocytes cultures. It was found that water and soil samples caused mutagenic effect in all model systems. They increased the frequency of revertants in Salmonella, the frequency of lethal mutations in Drosophila chromosomes, and the frequency of chromosome aberrations in cultures of human and sheep lymphocytes. Although a genotoxic effect was demonstrated for each of these models, various models showed different sensitivity to the effects of pesticides and they varied degree of response. The association between the total content of OCPs in soil and the level of mutations for different model systems was discovered.
chromosomal aberrations , ecological monitoring , genotoxic effect , lethal mutations , model objects , organochlorine pesticides , risk assessment , short screening tests (SST)
Text of the article Перейти на текст статьи
Institute of Genetics and Physiology, Department of molecular genetics, Almaty, Kazakhstan
Institute of Genetics and Physiology, Department of genetic monitoring, Almaty, Kazakhstan
Institute of Genetics and Physiology, Department of animal genetics and cytogenetics, Almaty, Kazakhstan
Institute of Genetics and Physiology, Department of experimental mutagenesis, Almaty, Kazakhstan
Kazakh National University by al-Farabi, biological faculty, Almaty, Kazakhstan
Institute of Plant Biology and Biotechnology, Department of plant physiology and biochemistry, Almaty, Kazakhstan
Institute of Genetics and Physiology
Institute of Genetics and Physiology
Institute of Genetics and Physiology
Institute of Genetics and Physiology
Kazakh National University by al-Farabi
Institute of Plant Biology and Biotechnology
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026