Diagnosis and Treatment of Severe Traumatic Brain Injury in Idiopathic Intracranial Hypertension Syndrome


Mirzabaev M. Dusembekov E. Akhanov G. Zhailaubayeva A. Karavayev V.
December 2023Elsevier Inc.

World Neurosurgery
2023#180e163 - e170 pp.

Objective: A topic of current research is the development of a new approach to the diagnosis and treatment of severe brain injury taking into consideration its main pathophysiological mechanism—idiopathic intracranial hypertension syndrome. The goal of this study was to identify Doppler patterns of unfavorable craniocerebral injury conditions to form a consistent algorithm of treatment measures to reduce secondary brain damage in patients with severe craniocerebral trauma. Methods: Transcranial Doppler imaging is a prospective method, which allows quick and noninvasive assessment of the intracerebral blood flow dynamics right at the patients bedside. Due to the operator-dependent nature of this method, clinical interpretation can often be contradictory. As a result, no clear criteria for therapy correction have yet been formulated based on this neuroimaging method. Results: Analysis of the therapy performed allowed us to specify the options for the hyperosmolar solutions for the correction of idiopathic intracranial hypertension syndrome. Conclusions: No statistically significant difference in effectiveness was shown between mannitol and hypertonic saline solutions.

Blood flow rate , Doppler pattern , Perfusion index , Transcranial Doppler , Treatment strategy

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Department of Neurosurgery, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan
Department of Neurosurgery, City Clinical Hospital No. 7, Almaty, Kazakhstan

Department of Neurosurgery
Department of Neurosurgery

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