Combined use of PRPP, diode laser and piezosurgery device improves reparative osteogenesis before dental implants placement
Menchisheva Y. Menzhanova D. Espolayeva A. Azhibekov A. Mirzakulova U. Sagatbayev A. Uglanov Z. Toregeldi G. Tsvetanov Tsokov K.
January 2025Elsevier (Singapore) Pte Ltd
Asian Journal of Surgery
2025#48Issue 1299 - 310 pp.
Objective: Current study evaluated whether use of the platelet-rich powder (PRPP), piezosurgery device and diode laser after removal of jawbones cysts and benign bone formations and extraction of impacted tooth could enhance bone regeneration before dental implantation. Methods: A study was conducted among 200 patients with post-surgical cavities (not exceeding 1.5 cm upon cystectomy, benign bone tumor removal and impacted tooth extraction) who underwent plasma powder, autograft, allograft, xenograft or beta-tricalcium phosphate augmentation procedures. Results: PRPP implantation in combination with irradiation of bone cavity by diode laser led to the formation of 15.40 % ± 2.1 of new bone. The activity of reparative osteogenesis on the bone surface was BB = 6.71 ± 1.3, which is 3 and 3.5 times higher than the mean value in comparison group after augmentation of xenograft and beta-tricalcium phosphate. The value of bone tissue resorption for main group patients was less pronounced (Ra.Oc = 25.20 % ± 2.1). The ratio between pro- and anti-inflammatory cytokines in the main group after 1, 7 and 30 days since surgical procedure was lower than the ratio of the corresponding cytokines in the comparison groups. Conclusion: The examination of computed tomograms, histological and morphometric analysis of bone tissue after trepanobiopsy, cytological analysis of swabs and enzyme immunoassay to determine local immunity indicated that the proposed method of treatment with the use of PRPP, the piezosurgery device and the diode laser has a positive effect: it helped to optimize reparative osteogenesis after filling post-surgical cavities and restore bone volume.
Bone defects , Laser , Piezoelectric device , Plasma powder
Text of the article Перейти на текст статьи
Department of Surgical Dentistry, S. D. Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan
Department of Histology, S. D. Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan
Dental Public Health, Medical University of Sofia, Sofia, Bulgaria
Department of Surgical Dentistry
Department of Histology
Dental Public Health
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026