Multifunctional role of Nobiletin in cancer chemoprevention


Malik D.-E.-S. Attar R. Ozbey U. Romero M.A. Yulaevna I.M. Purenovic J.
2022Cellular and Molecular Biology Association

Cellular and Molecular Biology
2022#68Issue 7200 - 207 pp.

The diversity of highly bioactive and pharmacologically active natural products which recognize essential biological targets having exquisite specificity, constitutes a massive pharmacological database for discovery of valuable drugs. The rapid accumulation of information has revealed chemopreventive role of nobiletin against wide variety of cancers. Recent efforts are now being expanded and new integrative omics technologies have illuminated continuously upgrading list of molecular mechanisms which underlie carcinogenesis and metastasis. In this mini-review, we explore the progress that has been made in the identification of promising molecular targets of nobiletin.

animal models , apoptosis , Cancer , cell Signaling

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Institute of Pharmaceutical Sciences, PUMHSW, Nawabshah, Pakistan
Department of Obstetrics and Gynecology, Yeditepe University, Turkey
Department of Nutrition and Dietetics, Faculty of Health Sciences, Munzur University, Turkey
Facultad de Medicina, Universidad Autónoma de Guerrero, Laboratorio de Investigación Clínica, Av. Solidaridad S/N, Colonia Hornos Insurgentes, Guerrero, Acapulco, CP 39300, Mexico
E. A. Buketov Karaganda University, Kazakhstan
Faculty of Technical Sciences, Cacak University of Kragujevac, Cacak, Serbia

Institute of Pharmaceutical Sciences
Department of Obstetrics and Gynecology
Department of Nutrition and Dietetics
Facultad de Medicina
E. A. Buketov Karaganda University
Faculty of Technical Sciences

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