Polymeric iodophors with poly(2-ethyl-2-oxazoline) and poly(N-vinylpyrrolidone): optical, hydrodynamic, thermodynamic, and antimicrobial properties


Makhayeva D.N. Filippov S.K. Yestemes S.S. Irmukhametova G.S. Khutoryanskiy V.V.
15 February 2022Elsevier Ltd

European Polymer Journal
2022#165

Formation of iodophors by interactions of poly(2-ethyl-2-oxazoline) and poly(N-vinylpyrrolidone) with molecular iodine dissolved in aqueous solutions with addition of potassium iodide and ethanol has been studied using a range of physicochemical techniques including UV–Vis spectroscopy, viscometry, dynamic light scattering, isothermal titration calorimetry and partitioning through semi-permeable membrane. It was established that poly(2-ethyl-2-oxazoline) exhibits greater ability to bind iodine compared to poly(N-vinylpyrrolidone). Despite the difference in the binding ability of these two polymers, their iodophors exhibited similar antimicrobial properties.

Antimicrobial properties , Iodine , Iodophors , Poly(2-ethyl-2-oxazoline) , Poly(N-vinylpyrrolidone) , Polymers

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Department of Chemistry and Chemical Technology, Al-Farabi Kazakh National University, Almaty, 050040, Kazakhstan
School of Pharmacy, University of Reading, Whiteknights, RG6 6DX Reading, United Kingdom
Pharmaceutical Sciences Laboratory, Faculty of Science and Engineering, Åbo Akademi University, Turku, 20520, Finland

Department of Chemistry and Chemical Technology
School of Pharmacy
Pharmaceutical Sciences Laboratory

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