Development of the global inflammatory bowel disease visualization of epidemiology studies in the 21st century (GIVES-21)


Mak J.W.Y. Sun Y. Limsrivilai J. Abdullah M. Kaibullayeva J. Balderramo D. Vergara B.I. Paudel M.S. Banerjee R. Hilmi I. Ali R.A.R. Wei S.C. Ng K.K. Altuwaijri M. Kelly P. Yamamoto-Furusho J.K. Kotze P.G. Ahuja V. Chong V.H. Dao H.V. Abbey Y. Ching J.Y.L. Ho A. Chan A.K.W. Bernstein C.N. Gearry R.B. Abreu M. Rubin D.T. Dotan I. Hracs L. Kaplan G.G. Ng S.C. Tao Y. Rong J. Chen X. Song H. Zhou C. Mu Y. Wei W. Bai X. Aniwan S. Kitiyakara T. Harinwan K. Bunchorntavakul C. Techathuvanan K. Kijdamrongthum P. Suttichaimongkol T. Wetwittayakhlang P. Simadibrata M. Syam A.F. Larasati D. Tedjasaputra T.R. Saragih A.H. Koncoro H. Kanabayeva A. Kongyrbayeva N. Kurmangaliyeva A. Laryushina Y. Perizat T. Venera A. Aidana K. Toscani I. Nicoloff L. Howe M. Khoo X.H. Heng W.C. Singh H. Chua A. Hong K.W. Weng M.-T. Lin W.-C. Lee H.-C. Chang C.-C. Lin C.-C. Le P.H. Huang T.-Y. Sun C.-K. Yeh H.-J. Ho Y.H. AlIbrahim B. Alahmari M. Hodges P. Nsokolo B. Awuku Y. Li M. Chan K.H. Man Y.W. Yun-Sze T.W. Fong A.
December 2023BioMed Central Ltd

BMC Medical Research Methodology
2023#23Issue 1

Background: There is a rapid increase in the incidence of inflammatory bowel diseases (IBD) in newly industrialized countries, yet epidemiological data is incomplete. We herein report the methodology adopted to study the incidence of IBD in newly industrialized countries and to evaluate the effect of environmental factors including diet on IBD development. Methods: Global IBD Visualization of Epidemiology Studies in the 21st Century (GIVES-21) is a population-based cohort of newly diagnosed persons with Crohn’s disease and ulcerative colitis in Asia, Africa, and Latin America to be followed prospectively for 12 months. New cases were ascertained from multiple sources and were entered into a secured online system. Cases were confirmed using standard diagnostic criteria. In addition, endoscopy, pathology and pharmacy records from each local site were searched to ensure completeness of case capture. Validated environmental and dietary questionnaires were used to determine exposure in incident cases prior to diagnosis. Results: Through November 2022, 106 hospitals from 24 regions (16 Asia; 6 Latin America; 2 Africa) have joined the GIVES-21 Consortium. To date, over 290 incident cases have been reported. All patients have demographic data, clinical disease characteristics, and disease course data including healthcare utilization, medication history and environmental and dietary exposures data collected. We have established a comprehensive platform and infrastructure required to examine disease incidence, risk factors and disease course of IBD in the real-world setting. Conclusions: The GIVES-21 consortium offers a unique opportunity to investigate the epidemiology of IBD and explores new clinical research questions on the association between environmental and dietary factors and IBD development in newly industrialized countries.

Diet , Environmental , Incidence , Prevalence

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Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong
The First Affiliated Hospital of Kunming Medical University, Kunming, China
Siriraj Hospital, Bangkok, Thailand
University of Indonesia, Depok, Indonesia
Research Institute of Cardiology and Internal Diseases, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan
Hospital Privado Centro Médico de Córdoba, Córdoba, Argentina
CASMU, Las Piedras, Uruguay
National Academy of Medical Sciences, Kathmandu, Nepal
Asian Institute of Gastroenterology, Hyderabad, India
University of Malaya, Kuala Lumpur, Malaysia
The National University of Malaysia, Bangi, Malaysia
National Taiwan University Hospital, Taipei, Taiwan
Conde S. Januário Hospital, Macao
Division of Gastroenterology, Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia
Tropical Gastroenterology & Nutrition Group, University of Zambia School of Medicine, Lusaka, Zambia
Instituto Nacional de Ciencias Médicas Y Nutrición Salvador Zubirá, Mexico City, Mexico
Pontifícia Universidade Católica Do Paraná (PUCPR), Curitiba, Brazil
All India Institute of Medical Sciences, Asian Institute of Gastroenterology, Hyderabad, India
RIPAS Hospital, Bandar Seri Begawan, Brunei Darussalam
Hanoi Medical University, Hanoi, Viet Nam
Euracare Hospital, Accra, Ghana
University of Manitoba IBD Clinical and Research Center, Winnipeg, MB, Canada
Department of Medicine, University of Otago, Christchurch, New Zealand
Department of Medicine, University of Miami Miller School of Medicine, FL, United States
Inflammatory Bowel Disease Center, University of Chicago Medicine, Chicago, IL, United States
Division of Gastroenterology, Rabin Medical Center, Petah-Tikva, Israel, Affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Division of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, AB, Canada
Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, The Chinese University of Hong Kong, Hong Kong

Department of Medicine and Therapeutics
The First Affiliated Hospital of Kunming Medical University
Siriraj Hospital
University of Indonesia
Research Institute of Cardiology and Internal Diseases
Hospital Privado Centro Médico de Córdoba
CASMU
National Academy of Medical Sciences
Asian Institute of Gastroenterology
University of Malaya
The National University of Malaysia
National Taiwan University Hospital
Conde S. Januário Hospital
Division of Gastroenterology
Tropical Gastroenterology & Nutrition Group
Instituto Nacional de Ciencias Médicas Y Nutrición Salvador Zubirá
Pontifícia Universidade Católica Do Paraná (PUCPR)
All India Institute of Medical Sciences
RIPAS Hospital
Hanoi Medical University
Euracare Hospital
University of Manitoba IBD Clinical and Research Center
Department of Medicine
Department of Medicine
Inflammatory Bowel Disease Center
Division of Gastroenterology
Division of Gastroenterology and Hepatology
Department of Medicine and Therapeutics

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