Burden of Ischemic Heart Disease in Central Asian Countries, 1990–2017
Lui M. Safiri S. Mereke A. Davletov K. Mebonia N. Myrkassymova A. Aripov T. Mirrakhimov E. Aghayan S.A. Gamkrelidze A. Naghavi M. Kopec J.A. Sarrafzadegan N.
April 2021Elsevier Ireland Ltd
IJC Heart and Vasculature
2021#33
Background: The burden of ischemic heart disease (IHD) is high. There is limited information on the burden of IHD in identified high risk areas like Central Asia (CA) which is comprised of Armenia, Azerbaijan, Georgia, Kazakhstan, Kyrgyzstan, Turkmenistan, Mongolia, Uzbekistan and Tajikistan. This study addresses the burden of IHD in CA at the regional and country levels. Methods: Using data from the latest iteration of the Global Burden of Disease Study (GBD), this study provides age-adjusted mortality, prevalence, and Disability Adjusted Life Years (DALYs) of IHD by sex in the CA region, and national levels for countries in this region from 1990 to 2017. Results: The CA region has a higher IHD burden than the rest of the world over the studied period. Amongst the countries within this region, age-standardized mortality and DALY rates in Uzbekistan are the highest not only in CA but worldwide, while Armenia consistently has the lowest IHD burden in CA. Unhealthy diet, high systolic blood pressure and LDL-cholesterol are the risk factors with the highest attributable IHD DALYs. Conclusion: Increasing burden of IHD over time in CA can be partially explained by the economic crisis in the 1990s. There is considerable variation in IHD DALY rates among countries in the CA region. The reasons for such differences are likely multifactorial such as differences in risk factors distribution, health care effectiveness, political, social and economic factors.
Burden of disease , Central Asia , DALY , Myocardial Ischemia , Risk factors
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School of Population & Public Health, University of British Columbia, Vancouver, Canada
Tuberculosis and Lung Disease Research Center, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran
Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Health Research Institute, The Faculty of Medicine, Al-Farabi Kazakh National University, Almaty, Kazakhstan
Department of Epidemiology and Biostatistics, Tbilisi State Medical University, Tbilisi, Georgia
School of Public Health, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan
Department of Public Health and Healthcare Management, Tashkent Institute of Postgraduate Medical Education, Tashkent, Uzbekistan
Kyrgyz State Medical Academy, Bishkek, Kyrgyzstan
National Center of Cardiology and Internal Disease, Bishkek, Kyrgyzstan
Department of Zoology, Yerevan State University, Yerevan, Armenia
National Center for Disease Control and Public Health, Tbilisi, Georgia
Department of Health Metrics Sciences, Institute for Health Metrics and Evaluation, School of Medicine, University of Washington, Washington, United States
Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
School of Population & Public Health
Tuberculosis and Lung Disease Research Center
Aging Research Institute
Cardiovascular Research Center
Health Research Institute
Department of Epidemiology and Biostatistics
School of Public Health
Department of Public Health and Healthcare Management
Kyrgyz State Medical Academy
National Center of Cardiology and Internal Disease
Department of Zoology
National Center for Disease Control and Public Health
Department of Health Metrics Sciences
Isfahan Cardiovascular Research Center
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