The immune response of Locusta migratoria manilensis at different times of infection with Paranosema locustae
Liu H. Wei X. Ye X. Zhang H. Yang K. Shi W. Zhang J. Jashenko R. Ji R. Hu H.
December 2023John Wiley and Sons Ltd
Archives of Insect Biochemistry and Physiology
2023#114Issue 4
Paranosema locustae is an entomopathogenic microsporidia with promising potential for controlling agricultural pests, including Locusta migratoria manilensis. However, it has the disadvantage of having a slow insecticidal rate, and how P. locustae infection impacts the host immune response is currently unknown. The present study investigated the effect of P. locustae on the natural immune response of L. migratoria and the activities of enzymes that protect against oxidative stress. Infection with P. locustae increased the hemocytes and nodulation number of L. migratoria at the initial stage of infection. The hemocyte-mediated modulation of immune response was also affected by a decrease in the number of hemocytes 12 days postinfection. Superoxide dismutase activity in locusts increased in the early stages of infection but decreased in the later stages, whereas the activities of peroxidase (POD) and catalase (CAT) showed opposite trends may be due to their different mechanisms of action. Furthermore, the transcription levels of mRNA of antimicrobial peptide-related genes and phenoloxidase activity in hemolymph in L. migratoria were suppressed within 15 days of P. locustae infection. Overall, our data suggest that P. locustae create a conducive environment for its own proliferation in the host by disrupting the immune defense against it. These findings provide useful information for the potential application of P. locustae as a biocontrol agent.
antibacterial peptide , immunity , Locusta migratoria manilensis , Paranosema locustae , protective enzymes
Text of the article Перейти на текст статьи
Xinjiang Key Laboratory of Special Species Conservation and Regulatory Biology, International Research Center of Cross-Border Pest Management in Central Asia, College of Life Sciences, Xinjiang Normal University, Xinjiang, Urumqi, China
Tacheng, Research Field (Migratory Biology), Observation and Research Station of Xinjiang, Xinjiang, China
Central for Prevention and Control of Prediction & Forecast Prevention of Locust and Rodent in Xinjiang Uygur Autonomous Region, Xinjiang, China
College of Plant Protection, China Agricultural University, Beijing, China
Institute of Zoology RK93, Al-Farabi Ave., Almaty, Kazakhstan
Xinjiang Key Laboratory of Special Species Conservation and Regulatory Biology
Tacheng
Central for Prevention and Control of Prediction & Forecast Prevention of Locust and Rodent in Xinjiang Uygur Autonomous Region
College of Plant Protection
Institute of Zoology RK93
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026