Evaluation of clinical research priorities in Asian intensive care units (ERA-ICU)

Li A. Nasa P. Myatra S.N. Shrestha G.S. Al-Fares A. Chan M.-C. Cho Y.-J. Egi M. Faruq M.O. Harmouche C. Hashemian S.M.R. Kharaba A. Konkayev A. Muchtar F. Nafees K.M.K. Naranpurev M. Son D.N. Ng P.Y. Mat-Nor M.B. Palo J.E. Uyar M. Zhang Z. Divatia J. Phua J. Arabi Y.M. Ling L. Vu C.H. Nguyen T.D. Le T.T.P. Mai T.X. Pham T.T.N. Hoang T.V. Nguyen D.T. Duong P.T. Nguyen K.T. Le M.H. Nguyen H.T. Dinh H.N. Nguyen H.H. Hoang H.H. Huynh D.Q. Luong C.Q. Ha B.S. Sherif R.M. Omar R. Mallat J. Barakat I. Ghanem A. Ruan S.-Y. Yang M.-C. Feng J.-Y. Wu J.-J. Hu H.-C. Cia C.-T. Loh W. Wong Y.-L. Lau Y.H. Tan Y.H. Chia Y.W. Lim S.L. Ho S. Gokhale R. Cove M. Venkatesan K. See K.C. Ramanathan K. Tsoong J. Kayambu G. Liew C. Lew C.C.H. Kayachandran B. Mukhopadhyay A. Al Duhailib Z. Alanazi S. Aljishi R.S. Alshahrani M. Hegazy M. Almekhlafi G. Awdallah F.F. Sanchez C. Alhammad A.M. Kim W.-Y. Lee S.I. Kim S. Park S. Chung K. Lim K.H. Bae J.-M. Lee J. Sim J.K. Yu B. Bigornia R.R. Convocar P. Patricio M. De Asis K. Gemarino J.B.T. Briones G. Gaerlan F.J. Noblezada-Uy D. Ashraf S. Ali M. Sohaib M. Kumar A. AlBahrani M. Begzjav T. Amartur T. Lkhagvadorj T. Narmandakh S.-E. Tegshee E. Samdan E. Lee Z.-Y. Yunos N.M. Hafizzi M. Hasan M.S. Chin J.Z. Bacha Z.A. Sange S. Aldosari D. Dauletbaev N. Konkayeva M. Azimova B. Atagi K. Yasuda H. Sitio N.D.K.S. Nurdin H. Pradian E. Joshi Z. Vaidyanathan R. Kuragayala S.D. Dixit S. Jha S. Mishra S. Shankar R. Shetty R.M. Mishra R. Amin P. Shah M. Govil D. Jagiasi B.G. Das B.P. Choudhuri A.H. Wong W.-T. Man M.Y. Ho K.-M. Shum H.P. Yu Y. Wang Y. Zhang Y. Wei X. Si L. Pan L.-A. Wang L. Liu J. Wang G. Chen D. Pan C. Lin B. Kashfi T. Morshed M. Basher A.
December 2025 BioMed Central Ltd

Journal of Intensive Care
2025 #13 Issue 1

Background: Practice and delivery of critical care in Asia varies according to healthcare structure, income setting, and cultural factors. Identifying research priorities specific to ICU patients and healthcare workers in Asia is needed to guide advancement of critical care in the region. Methods: This was an international cross-sectional survey study with adapted methods from nominal group techniques. All members of the Asian Critical Care Clinical Trials (ACCCT) Group were invited to submit research question suggestions. Submitted research questions were combined into summarized research questions, grouped into research themes, and individually ranked by number of mentions based on the original question submission (popularity). National and Regional Representatives rated the top 15% most popular summarized research questions by pre-defined importance and feasibility criteria. Results: Between September 20, 2024 and December 10, 2024, 160 of 228 general members of the ACCCT Group (response rate 70.2%) participated in this survey study. The participants were from 112 hospitals across 24 countries and regions within Asia. Participants submitted 408 research questions, which were categorized into 15 themes and combined into 197 summarized research questions. The top three themes, as ranked by the number of mentions, were infection/sepsis, general ICU care, and structure/training/staffing/teamwork/safety. A threshold of 4 mentions was used to identify 26 summarized research questions that represented the top 15% most popular questions. Research questions related to sepsis and acute respiratory distress syndrome were ranked most important and feasible across the region. Conclusion: Twenty-six of the most popular research questions in critical care were identified by Asian ICU workers and researchers to drive research agenda in Asia for the next decade.

Agenda , Clinical study , Critical care , Feasibility , Importance , Interest , International , Investigation , Relevance

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Department of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore, Singapore
Department of Intensive Care Medicine, Woodlands Health, Singapore, Singapore
Critical Care Medicine, NMC Specialty Hospital, Dubai, United Arab Emirates
Integrated Critical Care Unit, New Cross Hospital, The Royal Wolverhampton NHS Trust, Wolverhampton, United Kingdom
Department of Anaesthesiology, Critical Care and Pain, Tata Memorial Hospital, Homi Bhabha National Institute, Maharashtra, Mumbai, India
Department of Critical Care Medicine, Institute of Medicine, Tribhuvan University Teaching Hospital, Bagmati, Kathmandu, Nepal
Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia
Department of Anesthesia, Critical Care Medicine, and Pain Medicine, Ministry of Health, Al-Amiri Hospital, Kuwait City, Kuwait
Kuwait Extracorporeal Life Support Program, Al-Amiri Center for Respiratory and Cardiac Failure, Ministry of Health, Kuwait City, Kuwait
Department of Critical Care Medicine, Taichung Veterans General Hospital, Taichung, Taiwan
Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan
Division of Critical Care and Respiratory Therapy, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South Korea
Department of Anesthesia, Kyoto University Hospital, Kyoto, Japan
Department of Critical Care Medicine & Emergency Medicine, United Hospital, Dhaka, Bangladesh
Pulmonary & Critical Care Division, Hotel Dieu de France, Saint Joseph University of Beirut, Beirut, Lebanon
Chronic Respiratory Disease Research Center, National Research Institute of Tuberculosis and Lung Diseases, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Department of Critical Care, King Fahad Hospital, Al Madinah Al Monawarah, Saudi Arabia
Anaesthesiology and Intensive Care Department, Astana Medical University, Astana, Kazakhstan
National Science Center of Traumatology and Orthopedia Named Batpenov, Astana, Kazakhstan
Department of Anesthesiology, Intensive Care and Pain Management, Medical Faculty, Hasanuddin University, South Sulawesi, Makassar, Indonesia
Ministry of Health, Department of Critical Care Medicine, RIPAS Hospital, Bandar Seri Begawan, Brunei Darussalam
Intensive Care Department, Mongolia Japan Hospital, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia
Center for Critical Care Medicine, Bach Mai Hospital, Hanoi, Viet Nam
Department of Emergency and Critical Care Medicine, Faculty of Medicine, VNU University of Medicine and Pharmacy, Vietnam National University, Hanoi, Viet Nam
Department of Emergency and Critical Care Medicine, Hanoi Medical University, Hanoi, Viet Nam
Critical Care Medicine Unit, The University of Hong Kong, Hong Kong
Department of Adult Intensive Care, Queen Mary Hospital, Hong Kong
Kulliyyah of Medicine, International Islamic University Malaysia, Pahang, Kuantan, Malaysia
Acute and Critical Care Institute, The Medical City, Pasig, Philippines
Department of Anaesthesiology and Intensive Care Unit, Ege University School of Medicine Hospital, Izmir, Turkey
Department of Emergency Medicine, Provincial Key Laboratory of Precise Diagnosis and Treatment of Abdominal Infection, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China
Critical Care Medicine, Lilavati Hospital and Research Centre, Mumbai, India
Division of Respiratory and Critical Care Medicine, Department of Medicine, Alexandra Hospital, National University Health System, Singapore, Singapore
Division of Respiratory and Critical Care Medicine, National University Hospital, National University Health System, Singapore, Singapore
Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
College of Medicine, King Abdullah International Medical Research Center, Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Hong Kong
Department of Intensive Care, Prince of Wales Hospital, Hong Kong

Department of Respiratory and Critical Care Medicine
Department of Intensive Care Medicine
Critical Care Medicine
Integrated Critical Care Unit
Department of Anaesthesiology
Department of Critical Care Medicine
Australian and New Zealand Intensive Care Research Centre (ANZIC-RC)
Department of Anesthesia
Kuwait Extracorporeal Life Support Program
Department of Critical Care Medicine
Department of Post-Baccalaureate Medicine
Division of Critical Care and Respiratory Therapy
Division of Pulmonary and Critical Care Medicine
Department of Anesthesia
Department of Critical Care Medicine & Emergency Medicine
Pulmonary & Critical Care Division
Chronic Respiratory Disease Research Center
Department of Critical Care
Anaesthesiology and Intensive Care Department
National Science Center of Traumatology and Orthopedia Named Batpenov
Department of Anesthesiology
Ministry of Health
Intensive Care Department
Center for Critical Care Medicine
Department of Emergency and Critical Care Medicine
Department of Emergency and Critical Care Medicine
Critical Care Medicine Unit
Department of Adult Intensive Care
Kulliyyah of Medicine
Acute and Critical Care Institute
Department of Anaesthesiology and Intensive Care Unit
Department of Emergency Medicine
Critical Care Medicine
Division of Respiratory and Critical Care Medicine
Division of Respiratory and Critical Care Medicine
Department of Medicine
College of Medicine
Department of Anaesthesia and Intensive Care
Department of Intensive Care

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