Bone mineral density disorders in subjects with seronegative spondylarthritis
Нарушения минеральной плотности костной ткани у лиц с серонегативными спондилоартритами
Latypova L.A. Yalaev B.I. Fathullina G.F. Zhamankulova D.G. Volchenkova M.V. Tyurin A.V.
2025Krasnoyarsk State Medical University
Siberian Medical Review
2025#2025Issue 55 - 12 pp.
This review presents data on the prevalence, diagnostic features, and pathogenesis mechanisms of decreased bone mineral density in patients with various spondyloarthritis-family diseases. It shows the conflicting nature of data on changes in the quantitative and qualitative characteristics of bone tissue in these patients, the role of cytokines, disease activity and inflammatory mediators. An analysis of the key genes associated with both the development of spondyloarthritis-type diseases and associated bone pathology has been performed. Key research and discussion points on this topic have been formulated as well as the importance of a personalised approach to diagnosis and treatment. This review was compiled through analysis of 59 articles by Russian and international authors from PubMed, eLibrary, and Medline Complete, primarily published within the past five years.
ankylosing spondylitis , autoinflammatory diseases , bone mineral density , cytokines , inflammatory mediators , osteoporosis , seronegative spondyloarthritis
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Republican Clinical Hospital named after G.G. Kuvatov, 132, Dostoevsky Str., Ufa, 450005, Russian Federation
National Medical Research Center for Endocrinology, 11, Dmitry Ulyanov Str., Moscow, 117292, Russian Federation
rheumatological department, rheumatologist Republican clinical hospital named after G.G. Kuvatova, 132, Dostoevsky Str, Ufa, 450005, Russian Federation
West Kazakhstan Medical University named after Marata Ospanova, 68, Maresyeva Str, Aktobe, 030019, Kazakhstan
Department of outpatient therapy, preventive medicine and general medical practice, Ryazan State Medical University, 9, Vysokovoltnaya Str, Ryazan, 390026, Russian Federation
department of internal diseases and clinical psychology, Bashkir State Medical University, 3, Lenina Str, Ufa, 450008, Russian Federation
Republican Clinical Hospital named after G.G. Kuvatov
National Medical Research Center for Endocrinology
rheumatological department
West Kazakhstan Medical University named after Marata Ospanova
Department of outpatient therapy
department of internal diseases and clinical psychology
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Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026