Risk of Infective Endocarditis Following Invasive Dental Procedures: A Systematic Review and Meta-Analysis


Kussainova Z. Kulmaganbetov M. Abiltayev A. Bulegenov T. Salikhanov I.
2024Frontiers Media SA

Public Health Reviews
2024#45

Objectives: This systematic review and meta-analysis aimed to synthesize evidence and determine the association between IE and dental procedures, including invasive and non-invasive procedures. Methods: We conducted a systematic search of PubMed, Google Scholar, and Cochrane databases for studies involving procedures such as tooth extraction, scaling, endodontic treatment, oral surgery, and periodontal treatment involving individuals aged ≥15 years. The primary outcome was the incidence of IE following these procedures. Results: An association was found between IE and invasive dental procedures (OR 1.49, 95% CI 1.25–1.76; p < 0.00001). Subgroup analysis showed an increased risk of IE following tooth extraction (OR 2.73, 95% CI 1.46–5.11; p = 0.002) and oral surgery (OR 6.33, 95% CI 2.43–16.49; p = 0.0002) in high-risk patients. Conclusion: Our study found a strong association between invasive dental procedures and increased IE risk, particularly for tooth extraction and oral surgery in high-risk individuals. Systematic Review Registration: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023488546, Identifier CRD42023488546. Copyright

endodontic treatment , infective endocarditis , invasive dental procedures , oral surgery , tooth extraction

Text of the article Перейти на текст статьи

Department of Public Health, Semey State Medical University, Semey, Kazakhstan
Centre for Eye and Vision Research Limited (CEVR), Hong Kong SAR, Hong Kong
Department of Surgery, University Hospital of Basel, Basel, Switzerland

Department of Public Health
Centre for Eye and Vision Research Limited (CEVR)
Department of Surgery

10 лет помогаем публиковать статьи Международный издатель

Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026