The effects of obesity on erectile and fertile health of men: A literary review
Konakbayev E.J. Zhanbyrbekuly U. Annarazov Y.A.
2024Kaz Med Print LLP
Reproductive Medicine (Central Asia)
2024#2024Issue 445 - 51 pp.
Obesity, which is developing very rapidly in the world, can decrease the quality of sperm in men. It affects the hypothalamic-pituitary-gonial axis and increases the number of hormones such as estrogen and leptin released from adipose tissue while decreasing testosterone and inhibin B. Obesity can lead to increased scrotal temperature, erectile dysfunction and DNA breaks of spermatozoa, and negatively affects the results of assisted reproductive techniques (ART) affects. Research is still needed to reliably analyze the effects of interventional surgery on erectile and reproductive function in obese men. The purpose of the study: Analysis of scientific works on the effect of male obesity on their erectile and fertility functions. Materials and Methods: Scientific articles were selected by keyword searches in the medical databases PUBMED, MEDLINE, and EMBASE. The search was conducted using the terms “metabolic syndrome,” “obesity,” and “erectile and reproductive functions in obese men” over the past decades. Results: Obesity is a metabolic syndrome characterized by a body mass index (BMI) of 30 kg/m² or higher, which makes the body vulnerable to various diseases. A decrease in sperm quality in men indicates a link between obesity and male infertility. Adipose tissue is a source of hormones such as ghrelin, leptin, orexin, adiponectin, obestatin, and adipokines. Conclusion: Studies have shown that obesity directly affects men’s erectile health. A decrease in the level of total and free testosterone, as well as a decrease in the level of inhibin B, can also be associated with a high level of estrogen. Physical exercises and diet should be the first line of treatment for obese men. In cases when the patient cannot follow these recommendations or when it is impossible to maintain the achieved result, it is necessary to resort to pharmacological therapy for obesity. In the case of morbid obesity, when special pharmacotherapy is ineffective, there is an opportunity to resort to bariatric operations. Interventional surgery is an opportunity for obese men to restore erectile function and conceive a child naturally or with the help of ART.
erectile dysfunction , metabolic syndrome , obesity , reproductive function in obese men
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Department of Special Surgical Disciplines, A. Yasawi International Medical University, Shymkent, Kazakhstan
Department of Urology and Andrology, Astana Medical University, Astana, Kazakhstan
Department of Surgery and Anesthesiology-Resuscitation, A. Yasawi International Medical University, Shymkent, Kazakhstan
Department of Special Surgical Disciplines
Department of Urology and Andrology
Department of Surgery and Anesthesiology-Resuscitation
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