Biochemical and neurological changes post-COVID-19: A focus on oxidative metabolism – A case–control study


Klyuyev D. Kaliyeva S. Kulbayeva Z. Tuleutayeva S.
July-September 2025Scientific Scholar LLC

Journal of Neurosciences in Rural Practice
2025#16Issue 3435 - 437 pp.

This study investigates biochemical alterations in patients recovering from COVID-19, with a particular emphasis on those experiencing persistent neurological symptoms. We compared oxidative stress markers and other biochemical indicators in post-COVID-19 individuals with those in a control group without a history of severe acute respiratory syndrome coronavirus 2 infection. The findings revealed significant shifts in oxidative and inflammatory biomarkers, especially in patients reporting neurological complaints. These alterations may underlie the persistence of such symptoms and suggest potential targets for future therapeutic interventions and diagnostic strategies.

Advanced oxidation protein products (AOPP) , COVID-19 , Malonic dialdehyde (MDA) , Neurological complications , Nitric oxide (NO) , Oxidative stress , Post-COVID , Reactive carbonyl derivatives of proteins (RCDP)

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Institute of Life Sciences, Karaganda Medical University, Non-Commercial Joint Stock Company, Karaganda, Kazakhstan
Department of Clinical Pharmacology and Evidence-Based Medicine, Karaganda Medical University, Non-Commercial Joint Stock Company, Karaganda, Kazakhstan
Department of Neurology, Psychiatry, and Rehabilitation Medicine, Karaganda Medical University, Non-Commercial Joint Stock Company, Karaganda, Kazakhstan
School of Dentistry, Karaganda Medical University, Non-Commercial Joint Stock Company, Karaganda, Kazakhstan

Institute of Life Sciences
Department of Clinical Pharmacology and Evidence-Based Medicine
Department of Neurology
School of Dentistry

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