FEATURES OF THE DEVELOPMENT OF THE REPRODUCTIVE SYSTEM BY USING GENETICALLY MODIFIED SOURCES (EXPERIMENTAL STUDY)

reproduqciuli sistemis ganviTarebis Taviseburebani genetikurad modificirebuli wyaroebis gamoyenebis pirobebSi (eqsperimentuli kvleva)
ОСОБЕННОСТИ РАЗВИТИЯ РЕПРОДУКТИВНОЙ СИСТЕМЫ ПРИ ИСПОЛЬЗОВАНИИ ГЕНЕТИЧЕСКИ МОДИФИЦИРОВАННЫХ ИСТОЧНИКОВ (ЭКСПЕРИМЕНТАЛЬНОЕ ИССЛЕДОВАНИЕ)
Kharissova N. Smirnova L. Kuzmin A. Ryspayeva G. Lepesbayeva G.
April 2021 Georgian Association of Business Press

Georgian Medical News
2021 #313 Issue 4 146 - 152 pp.

The rapid development of molecular biology and genetic engineering contributes to the creation of plants with desired properties in a short time. One of the aspects of the study of genetically modified organisms (GMO) and genetically modified products (GMP) is the study of their impact on humans, animals and the environment. Subject of research - changes in the morph functional indicators of the reproductive system of mice. The relevance of the chosen topic is due to the importance of the reproductive system for the reproduction of a healthy generation, capable of developing normally and continuing its race. Purpose of the study - to identify the effect of GMOs on the reproductive system of mice. Cultivation of three groups of laboratory mice using transgenic feed (genetically modified soybean meal) and obtaining biological material for research. Determination of the presence of genetically modified sources (GMS), genetically modified organisms (GMO) in food and feed products using the polymerase chain reaction (PCR). Morphometric study of the obtained material and biometric data processing. It has been shown that the consumption of feed by animals prepared on the basis of genetically modified plants does not affect the reproductive functions of the parental generation; but at the same time there was an inhibition of the growth rate and the process of formation of the gonads of the descendants of the first and, especially, the second generation; the second generation of offspring, eating only soybean meal, had defective reproductive qualities and high mortality. Second-generation mice eating genetically modified soybean meal are at greater risk than second-generation mice eating traditional diets.

body weight; reproductive system , GM-soy , GMO , GMS , laboratory mice

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Karaganda Medical University, Department of Morphology and Physiology, Karaganda, Kazakhstan
Kostroma State University named after N. Nekrasov, Russian Federation
Department of Physical Culture and Sports, Kostroma, Russian Federation
Department of Biology and Ecology, Kostroma, Russian Federation

Karaganda Medical University
Kostroma State University named after N. Nekrasov
Department of Physical Culture and Sports
Department of Biology and Ecology

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