Hepatitis E virus sero-prevalence among pregnant women in Khyber Pakhtunkhwa Pakistan

Khan S.A. Khan Z. Alam Z. Sana H. Ali M. Zaman N. Ualiveya D. Rizwan M. Suleman M.
December 2022 Elsevier Inc.

Clinical Immunology Communications
2022 #2 79 - 82 pp.

In Pakistan, the Hepatitis E virus (HEV) is prevalent. HEV exposure is deadly during pregnancy, with high infection rates in both the mother and the baby, even in asymptomatic situations. The researcher examined HEV-negative pregnant women with acute hepatitis or increased renal characteristic assessments at 12 medical sites in Khyber Pakhtunkhwa, Pakistan, to identify maternal and fetal disease risks from August to December 2018. Except for one during the entire pregnancy, twenty-five of the 135 females were HEV-free and in the perinatal period. HEV infection was found in 0.19% of newly pregnant women. Also, 11 cases of forcible induction of labor, 7 cases of normal labor, 5 cases of normal labor (full-term), 2 cases of death, and 1 case of intrauterine death were reported before going to the doctor a girl had an abortion. There were eight postpartum deaths: five from infections, four from miscarriages, and two from miscarriages. While 18 mothers who survived voluntarily or intentionally induced abortions and three women who continued to get pregnant but did not deliver died as a result of abortion. The current study found that HEV infection during pregnancy raised the death rate by 14.2%.

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Center for Biotechnology and Microbiology, University of Swat, Pakistan
University of Chinese Academy of Sciences, Beijing, 100049, China
State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China
Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, China
Faculty of Biology and Biotechnology, Al-Farabi Kazakh National University, Almaty, 050040, Kazakhstan

Center for Biotechnology and Microbiology
University of Chinese Academy of Sciences
State Key Laboratory of Respiratory Disease
Chengdu Institute of Biology
Faculty of Biology and Biotechnology

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