A novel fabrication of microfluidic device for generation of multiple emulsions
Khalilnezhad A. Sahraei E. Cortes F.B. Riazi M.
1 December 2023American Institute of Physics Inc.
Review of Scientific Instruments
2023#94Issue 12
Due to extensive applications of microfluidic devices, manufacturing of these apparatus has recently been noticed. Production of multiple emulsions is one of the main goals of manufacturing microfluidic devices. Design and fabrication of microfluidics are functions of the size of emulsion droplets, properties of fluids applied for emulsification, and considered stability for emulsions. In this article, we have manufactured a novel microfluidic device using simple fabrication and accessible materials. Capillary tubes, PTFE (polytetrafluoroethylene) chassis, a medical needle of gauge 32, and O-rings are the primary materials used to produce this device. The production procedure is explained completely, and all the drawings are represented. Concerning probable interactions between glues and flowing fluids, we tried to fabricate and seal the device without applying chemical agents. The device is tested by n-heptane and deionized water to produce multiple water-in-oil-in-water (W/O/W) emulsions. A sensitivity analysis on the rate of injection is performed. Considering the HLB (hydrophilic-lipophilic balance) as an important property of emulsifiers, the effects of two different types of emulsifiers (sodium dodecyl sulfate with HLB of 40 and glycerol monostearate with HLB of 3.8) at various concentrations are investigated. Due to the results, the injection rate of the mediate phase should be less than half of the outer phase for the formation of emulsions. Consequently, the rate of injection for the inner phase should be less than half of that for the mediate phase. The simplicity of production and accessible raw materials could be considered as the strengths of our microfluidic device.
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Faculty of Petroleum and Natural Gas Engineering, Sahand University of Technology, Tabriz, Iran
Grupo de Investigación en Fenómenos de Superficie-Michael Polanyi, Departamento de Procesos y Energía, Facultad de Minas, Universidad Nacional de Colombia, Sede Medellín, Medellín, 050034, Colombia
School of Mining and Geosciences, Nazarbayev University, Kabanbay Batyr 53 Astana, 010000, Kazakhstan
Faculty of Petroleum and Natural Gas Engineering
Grupo de Investigación en Fenómenos de Superficie-Michael Polanyi
School of Mining and Geosciences
10 лет помогаем публиковать статьи Международный издатель
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