Effectiveness of uterine artery embolization in uterine fibroids: A literature review
Kenzhebayeva A.Zh. Turdunova G.S. Ybyrayymbek A.K. Zhenisova A.T.
30 September 2025Kaz Med Print LLP
Reproductive Medicine (Central Asia)
2025#2025Issue 3
Relevance: Uterine fibroids are one of the most common benign neoplasms of the female reproductive system, accompanied by a variety of clinical symptoms such as bleeding, pain, and fertility disorders. In recent decades, uterine artery embolization (UAE) has established itself as a minimally invasive alternative to traditional surgical treatments. This review summarizes current data on the effectiveness of UAE, evaluates the dynamics of fibroid size reduction, examines clinical symptoms and the safety of the method, and studies issues related to the preservation of reproductive function. The study aimed to systematize current research data on the effectiveness of UAE in the treatment of uterine fibroids, evaluate the advantages and limitations of UAE, and identify directions for future research. Materials and Methods: To prepare this review, publications available in international and Russian databases (PubMed, eLibrary.ru, Google Scholar) over the past 10 years were analyzed. The included studies assessed clinical outcomes, the dynamics of fibroid volume reduction, the safety of the procedure, and its impact on reproductive function. Results: Numerous studies show that UAE statistically significantly decreases the volume of fibroids by 40-70% for 6-12 months. Several studies indicate a correlation between the degree of embolization and clinical improvement: patients note a decrease in menstrual bleeding, a decrease in pain, and an overall improvement in well-being. The reviewed literature demonstrates the high effectiveness of UAE in reducing fibroid size and improving patients’ quality of life. However, questions remain regarding long-term fertility preservation and standardized patient selection. Conclusion: UAE is one of the uterus-preserving methods for the treatment of uterine fibroids. This method has shown good results in reducing fibroid size and regressing undesirable symptoms, with a comparatively low rate of procedural complications. The most common adverse events are post-embolization syndrome (mild fever, pain, general malaise), which usually resolves within a few days. Rare complications include infections, menstrual irregularities, and, in some cases, the need for re-intervention. These limitations highlight the need for further research.
reproductive function , uterine artery embolization (UAE) , uterine fibroids
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Department of Obstetrics, Gynecology and Perinatology, Karaganda Medical University, Karaganda, Kazakhstan
Department of Obstetrics
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