Application of autologous stem cells in the treatment of ischaemic cardiomyopathy with heart failure after myocardial infarction
Kemelbekov B. Amanzholkyzy A. Saparbayev S. Stankevicius E.
2025M/S GN Corporation Co. Ltd
Journal of Stem Cells and Regenerative Medicine
2025#21Issue 103 - 10 pp.
The proposed topic is important because it helps find a lot of problems that happen when cardiovascular diseases are passed on along with fibrosis and the link between stem cells and myocardial regeneration. This study aims to investigate the effectiveness of autologous stem cells in the treatment of post-infarction myocardial changes. Statistical, bibliographic, and bibliosemantic research methods and scientific literature for the last 6 years were used to achieve the purpose. Cardiovascular diseases hold the highest prevalence and mortality rates, second only to the number of accidents. Today, there are many methods in the fight against coronary heart disease. However, drug therapy is the least effective, and instrumental methods are too invasive and entail several complications and side effects. Therefore, conducting detailed research on the impact of stem cells on the myocardium affected by infarction presents a challenge. Stem cell transplantation, which includes autologous bone marrow stem cells, typically leads to noticeable and significant changes in cardiac hemodynamic parameters and rheological properties. The development of autologous bone marrow stem cells during the angiogenesis process substantiates such metamorphoses. In addition, factors such as vascular endothelial growth factor and the whole list of coagulogram indicators may influence these changes. The practical significance of the raised subject is using stem cell therapy as an alternative, less invasive method in the fight against postinfarction myocardial changes.
Bone marrow , Cardiovascular system , Fibrosis , Pluripotent cells , Regeneration
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Department of Normal Physiology, West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan
West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan
Department of Normal Physiology, Lithuanian University of Health Sciences, Kaunas, Lithuania
Department of Normal Physiology
West Kazakhstan Marat Ospanov Medical University
Department of Normal Physiology
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026