Experience in a comprehensive pre-test risk assessment of thromboembolic complications in surgical patients with a high risk of congenital thrombophilia
Karazhanova L.K. Isakhanova S.A.
4 December 2021Hemostasis and Rheology LLC
Tromboz, Gemostaz i Reologiya
2021#2021Issue 468 - 74 pp.
Background. Every year, about a third of deaths from venous thromboembolic complications (VTEC) in the world occur among surgical patients. Traditional risk assessment is not always suitable for surgical patients due to the wide disparity of age groups, the presence of patients with various thrombophilic conditions, high risks of forthcoming interventions, and low medical staff alertness. The solution is to find the best tools for pre-test diagnostics. Objectives: to analyze the results of a comprehensive pre-test assessment of VTEC risk in surgical patients with a high risk of congenital thrombophilia. Patients/Methods. We examined 35 patients with one of VTEC manifestations (main group) and 55 patients who had a history of VTEC or VTEC episode in first blood line relatives under the age of 50 (control group). Testing was carried out according to Geneva, Wells, and Caprini scales with subsequent analysis. Parus-test was used to detect the disturbances in protein C system. Results. The pre-test assessment using the Caprini scale and the normalized ratio (NR) of Parus-test showed a high risk of VTEC in patients of both groups. Conclusions. Testing with the Caprini scale and NR of Parus-test showed good results for assessment of VTEC risks and for a qual-itative selection of VTEC prevention method in surgical patients.
Congenital thrombophilias , Prophylaxis , Risk assessment , Surgical patients , Venous thromboembolic complications
Text of the article Перейти на текст статьи
Semey Medical University, 103 Abay Str., Semey, 071400, Kazakhstan
Semey Medical University
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026