Maternal obesity and placental pathology: A prospective cohort study of pregnancy outcomes
Karataeva S.K. Orynbek B.A. Pankova A.N. Khanazarova A.E. Kenzhaeva D.I.
1 July 2025Kaz Med Print LLP
Reproductive Medicine (Central Asia)
2025#2025Issue 2126 - 132 pp.
Relevance: Obesity among women of childbearing age is becoming more common, and its effect on pregnancy is of particular interest to experts. One of the key aspects affected by maternal overweight is the condition of the placenta, the organ that provides communication between mother and fetus. With obesity, disorders in the structure and function of the placenta are often noted, which can lead to various complications, such as delayed intrauterine development, preeclampsia, and premature birth. The study aimed to investigate the relationship between maternal obesity and impaired placental vascularization and to determine how these changes may contribute to the development of preeclampsia in pregnant women. Materials and Methods: This prospective cohort observational study included 200 pregnant women divided into three groups: 1. Normal-weight group (BMI 18.5-24.9) – 70 women. 2. Overweight group (BMI 25-29.9) – 65 women. 3. The obese group (BMI ≥30) – 65 women. Results: Maternal obesity significantly increases the risk of placental vascularization disorders and complications such as preeclampsia, low birth weight in newborns, and preterm labor. The risks increase as a womans body weight increases, with differences being particularly pronounced between the obese and normal-weight groups. Conclusion: Maternal obesity is associated with pronounced disorders of placental vascularization, which can contribute to the development of preeclampsia and an increase in the frequency of adverse pregnancy outcomes, such as premature birth and low birth weight. The study highlights the need for early diagnosis and prevention of preeclampsia in obese women, as well as more careful monitoring of the placenta during pregnancy.
Doppler ultrasound , obesity , perinatal outcomes , placental pathology , placental vascularization , preeclampsia
Text of the article Перейти на текст статьи
Department of Obstetrics, Gynecology and Perinatology, Karaganda Medical University, Karaganda, Kazakhstan
Kazakh-Russian Medical University, Almaty, Kazakhstan
Department of Obstetrics
Kazakh-Russian Medical University
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026