Fertility-sparing in cancer patients
Karakaş S. Kaya C. Schäfer S.D. Mikuš M. Terzic M. Abdullaev B. Andrisani A.
15 August 2021IMR Press Limited
Clinical and Experimental Obstetrics and Gynecology
2021#48Issue 4787 - 794 pp.
Objective: This review aimed to investigate and summarize the current evidence on fertility-sparing options in cancer patients. Mechanism: Fertility preservation methods are becoming popular through the improved prognosis of cancer patients at a younger age and early diagnostic tools. However, currently, more and more women are suffering from iatrogenic ovarian failure and fertility loss because of cancer treatment. Most treatments have been used for hematological malignancies, but different gynecological cancers can be eligible. Findings in brief : Fertility preserving strategies such as oocyte and embryo cryopreservation, ovarian tissue preservation, ovarian transposition, and aspiration of ovarian follicles are the methods that could be suggested to the patients. The current knowledge supports oocyte and embryo cryopreservation as feasible, safe, and effective treatment approaches for cancer patients seeking fertility preservation. Conclusions: Robust evidence is still needed to prove the effectiveness of cryopreservation of the ovarian tissue and ovarian follicle aspiration approaches since these techniques are still in early their steps.
Cryopreservation , Infertility , Organ transplants , Ovarian neoplasms
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Department of Gynecological Oncology, University of Health Sciences, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, 34147, Turkey
Department of Obstetrics and Gynecology, Acibadem Mehmet Ali Aydinlar University, Acibadem Bakirkoy Hospital, Istanbul, 34147, Turkey
Department of Obstetrics and Gynecology, University of Münster, Münster, 48149, Germany
Department of Obstetrics and Gynecology, University Hospital Center Zagreb, Zagreb, 10000, Croatia
Department of Medicine, Nazarbayev University, School of Medicine, Nur-Sultan, 020000, Kazakhstan
Clinical Academic Department of Womens Health, National Research Center of Mother and Child Health, University Medical Center, Nur-Sultan, 020000, Kazakhstan
Department of Obstetrics Gynecology and Reproductive Sciences, University of Pittsburgh, School of Medicine, Pittsburgh, 15213, PA, United States
Department of International Relations and Scientific Development, Akfa University, Tashkent, 100190, Uzbekistan
Department of Womens and Childrens Health, University of Padua, Padua, 35122, Italy
Department of Gynecological Oncology
Department of Obstetrics and Gynecology
Department of Obstetrics and Gynecology
Department of Obstetrics and Gynecology
Department of Medicine
Clinical Academic Department of Womens Health
Department of Obstetrics Gynecology and Reproductive Sciences
Department of International Relations and Scientific Development
Department of Womens and Childrens Health
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