Obtaining New Biocompatible Composite Materials with Antibacterial Properties Based on Diatomite and Biologically Active Compounds
Kabieva S. Zhumanazarova G. Zhaslan R. Zhumabayeva G. Ukhov A. Fedorishin D. Gubankov A. Tarikhov F. Yerkhan O. Irina K. Yerkassov R. Bakibaev A.
April 2024Multidisciplinary Digital Publishing Institute (MDPI)
Molecules
2024#29Issue 7
This study aimed to create new composite materials based on diatomite—a non-organic porous compound—through its surface modification with bioactive organic compounds, both synthetic and natural. Chloramphenicol, tetrahydroxymethylglycoluril and betulin were used as modifying substances. Composite materials were obtained by covering the diatomite surface with bioactive substance compounds as a solution and material dispersion in it. The materials were characterized by IR spectroscopy, SEM and X-ray photoelectron spectroscopy. For the biocomposites, the hemolytic effect, plasma proteins’ adsorption on the surface and the antibacterial activity of the obtained materials were studied. Results show that the obtained materials are promising for medicine and agriculture.
antibacterial activity , betulin , biocompatible materials , chloramphenicol , diatomite , tetrahydroxymethylglycoluril
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Department of Chemical Technology and Ecology, Karaganda Industrial University, Temirtau, 101400, Kazakhstan
Faculty of Natural Sciences, L.N. Gumilyov Eurasian National University, St. Satbaeva 2, Almaty District, Astana, 010000, Kazakhstan
Chemical Faculty, National Research Tomsk State University, Arkady Ivanov St. 49, Tomsk, 634028, Russian Federation
Department of Chemical Technology and Ecology
Faculty of Natural Sciences
Chemical Faculty
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026