Bentonite-Based Composites in Medicine: Synthesis, Characterization, and Applications
Kabdrakhmanova S.K. Kerimkulova A.Z. Nauryzova S.Z. Aryp K. Shaimardan E. Kukhareva A.D. Kantay N. Beisebekov M.M. Thomas S.
June 2025Multidisciplinary Digital Publishing Institute (MDPI)
Journal of Composites Science
2025#9Issue 6
One of the most interesting and poorly studied carriers of medicinal substances is the polymer clay composite material (PCCM). Bentonite clays are used in pharmacy for the manufacturing of various dosage forms, as well as in the adsorption of drugs to slow their release. Polymer–clay nanocomposites have demonstrated significantly improved properties compared to pure polymers. A review of recent scientific advances has shown promising results regarding the application of polymer–clay materials in medicine and bioengineering, particularly in the development of carrier sorbents with prolonged action for controlled drug release. As a result, interest in polymer–clay systems is steadily growing and gaining momentum. This paper focuses on the structure and properties of bentonite clays, including their sorption, ion exchange, binding, and rheological properties. The methods for preparing intercalated and exfoliated nanocomposites, such as radical intercalative polymerization in situ on clay surfaces, are reviewed. Furthermore, the improved efficacy and exposure times of PCCMs, combined with their enhanced bactericidal properties, are analyzed for the creation of universal and multifunctional preparations for medical use.
bentonites , clay modification , exfoliated nanocomposites , intercalated nanocomposites , montmorillonite , organoclay , polymer composites , sorption properties
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Department of Chemical Processes and Industrial Ecology, Satbayev University, Almaty, 050013, Kazakhstan
Department of Chemical and Biochemical Engineering, Satbayev University, Almaty, 050013, Kazakhstan
Scientific Center of Composite Materials, Almaty, 050026, Kazakhstan
Higher School of IT and Natural Sciences, Amanzholov University, Ust-Kamenogorsk, 070020, Kazakhstan
Science & Technology Research Park, Mahatma Gandhi University, Kerala, Kottayam, 686560, India
Department of Chemical Processes and Industrial Ecology
Department of Chemical and Biochemical Engineering
Scientific Center of Composite Materials
Higher School of IT and Natural Sciences
Science & Technology Research Park
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