Numerical study of the distribution of sprayed particle deposition in different human nasal cavity
Issakhov A. Abylkassymova A.
2025Taylor and Francis Ltd.
Numerical Heat Transfer; Part A: Applications
2025#86Issue 197006 - 7028 pp.
This article numerically investigates the propagation of nasal sprayer particles to improve drug delivery through the nasal cavity. Topical nasal sprays are among the generally dictated therapeutic agents for sinus disorders in humans. However, the inconsistency of instructions indicates a lack of definitive knowledge of the best methods for nebulizing drugs. This study suggested nasal spray angles that could improve local drug delivery to the affected area compared to common spray methods. In this study, various particle diameters and aerosol flow angles are examined to evaluate the optimal efficiency of drug supply into the nasal cavity. Computational simulation of a particle-laden flow is performed in the nasal cavity of a healthy patient and a patient with rhinitis. The numerical results of this work open up new possibilities for proposing an alternative user-friendly plan that can essentially improve local drug delivery to the human nasal cavity.
Air flow in the human respiratory system , alveolar state , heat exchange in the nasal cavity , Navier–Stokes equation , rhinitis
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Kazakh British Technical University, Almaty, Kazakhstan
Al-Farabi Kazakh National University, Almaty, Kazakhstan
Kazakh British Technical University
Al-Farabi Kazakh National University
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026