Clinical heterogeneity in Fabry disease: A clinical case


Issabekova A. Mashkunova O.
2023National Scientific Medical Center

Journal of Clinical Medicine of Kazakhstan
2023#20Issue 468 - 70 pp.

Fabry disease is an orphan lysosomal storage disease characterized by progressive organ damage. Considering that the disease is rare, the low awareness of doctors about this pathology leads to late diagnosis of the disease and untimely pathogenetic therapy. Clinical case of late (relative to clinical manifestation) diagnosis of the “classical” phenotype of Fabry Disease in a male patient with cardiac and renal damage and typical early presentations such as neuropathic pain, angiokeratomas, hypohidrosis.

agalsidase , Fabry disease , globotriaosylceramide , α-galactosidase

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Cardiology Department, Scientific Institution of Cardiology and Internal Diseases, Almaty, Kazakhstan
Therapeutic Department, National Medical University, Almaty, Kazakhstan

Cardiology Department
Therapeutic Department

10 лет помогаем публиковать статьи Международный издатель

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