The levels of oxidative stress in a combination of stress factors
Ilderbayev O. Okassova A. Rakhyzhanova S. Ilderbayeva G. Zhazykbayeva L.
1 August 2022Carol Davila University Press
Journal of Medicine and Life
2022#2022Issue 8927 - 931 pp.
We studied the effect of the combined action of ionizing radiation and induced immobilization stress on the lipid per-oxidation process and antioxidant protection of organs (mesenteric lymph nodes, spleen, adrenal glands, thymus, and liver) and immune cels-the blood lymphocytes. Results were obtained on the role of free-radical oxidation in combination with exposure to ionizing radiation and immobilization stress at an early stage in the experiment. Gamma radiation in the acute period resulted in significant changes in lipoperoxidation and antioxidant systems. The first period of immobilization stress was marked by the imbalance of LPO-AOS systems disturbance with an accumulation of toxic compounds in tissues which had affected their function. The combined sublethal gamma radiation and immobilization stress disturbed the functional activity of adaptive systems of the body in the early stage of adaptation syndrome. Furthermore, the results show the dominant role of ionizing radiation in it.
antioxidant protection , combined effects , free-radical processes , immobilization stress , radiation
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Department of General Biology and Genomics, Faculty of Natural Sciences, L.N. Gumilyov Eurasian National University, Nur-Sultan, Kazakhstan
Department of Physiological Disciplines, Semey Medical University, Semey, Kazakhstan
Department of Biotechnology and Microbiology, Natural Science Faculty, NCJSC L.N. Gumilyov Eurasian National University, Nur-Sultan, Kazakhstan
Department of General Biology and Genomics
Department of Physiological Disciplines
Department of Biotechnology and Microbiology
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