D-hypovitaminosis in working age patients with diseases of the respiratory organs: the risks and prevention

D-гиповитаминоз у пациентов с заболеваниями органов дыхания в трудоспособном возрасте: риски и профилактика
Ibrayeva L.K. Rybalkina D.Kh. Evmenova O.A. Turdaly F.M. Ibragim Z.T.
2022 Pulmonology LLC

Pulmonologiya
2022 #32 Issue 6 891 - 898 pp.

D-hypovitaminosis in the working-age population is quite common in industrialized countries, especially when it comes to patients with chronic diseases, including respiratory ones. The role of vitamin D in calcium and bone homeostasis is well known. In recent years, vitamin D has been recognized to modulate many processes and regulatory systems involved in the immune response and reparative processes, in addition to the classic function of this vitamin. Aim. A review of the prevalence of D-hypovitaminosis in the working-age population with respiratory diseases was conducted using the PubMed, Web of Science, Scopus, clinicaltrials.gov databases for 2014-2019. Results. Epidemiological and experimental studies have shown that low serum vitamin D is associated with impaired lung function, an increase in the incidence of inflammatory, infectious, or neoplastic diseases, which include asthma, COPD, and cancer. Conclusion. Knowledge of direct pathogenetic relationships between vitamin D levels and lung diseases is currently limited, although there is a number of studies that highlight the relevance of this relationship. A number of studies are contradictory in their results, which requires further study of the role of vitamin D levels in the pathogenesis of respiratory diseases and the need for its inclusion in the essential therapy to improve the effectiveness of treatment and accuracy of the prognosis. However, large-scale screening studies of vitamin D level for the purpose of its correction are costly, even with a single measurement.

respiratory diseases , risk factors , vitamin D deficiency , working-age population

Text of the article Перейти на текст статьи

Karaganda Medical University, ul. Gogolya 40, Karaganda, 110000, Kazakhstan

Karaganda Medical University

10 лет помогаем публиковать статьи Международный издатель

Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026