Solid-Phase Microextraction for the Quantification of Acetophenone Migrated to Air and Water from Toys and School Supplies
Ibragimova O.P. Omarova A. Bukenov B. Baimatova N.
October 2023Pleiades Publishing
Journal of Analytical Chemistry
2023#78Issue 101414 - 1425 pp.
Abstract: Acetophenone is a reagent used in various consumer products, including fragrance chemicals in toys and childcare products. Contact with acetophenone-containing materials can harm human health, and therefore acetophenone migration levels should be controlled. A new procedure for the quantification of acetophenone migrated to air and water from toys and school supplies using solid-phase microextraction and gas chromatography with mass spectrometric detection is proposed. The optimal combination of acetophenone response and its relative standard deviations was achieved for air samples after 10-min extraction at 25°C and for water samples after the addition of 3.5 g of salt, agitation/preincubation at 500 rpm for 5 min at 60°C, and 20-min extraction by polydimethylsiloxane/divinylbenzene fiber. The developed procedure provided linear calibration with R 2 > 0.996 at 1–50 µg/m3 in air and 1–20 µg/L in water, and low limits of detection and quantification of acetophenone in the air (0.01, 0.04 µg/m3) and water (0.01, 0.03 µg/L). Spike recoveries of acetophenone were 109–116% for air and 90–111% for water. Acetophenone concentrations migrated from toys and school supplies into the air ranged from 0.6 to 1.5 µg/m3, except for eraser type II (9.7 µg/m3) which exceeded the maximum permissible concentration by 3.2 times. Acetophenone concentrations migrated to water were 1.3–3.5 µg/L.
acetophenone , air , rubber-latex compositions , solid-phase microextraction , water
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Center of Physical Chemical Methods of Research and Analysis, Faculty of Chemistry and Chemical Technology, Al-Farabi Kazakh National University, Almaty, A05H2B1, Kazakhstan
The Republican State Enterprise “Kazakhstan Institute of Standardization and Metrology” of the Committee for Technical Regulation and Metrology of the Ministry of Trade and Integration of the Republic of Kazakhstan, Astana, Z05K5H3, Kazakhstan
Center of Physical Chemical Methods of Research and Analysis
The Republican State Enterprise “Kazakhstan Institute of Standardization and Metrology” of the Committee for Technical Regulation and Metrology of the Ministry of Trade and Integration of the Republic of Kazakhstan
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