Impact of Airflow Disturbance from Human Motion on Contaminant Control in Cleanroom Environments: A CFD-Based Analysis


Guldana A. Niyetbay S. Zhanguzhinov A. Kassabekova G. Jartayeva D. Alimova K. Zhakapbayeva G. Bostandyk K.
July 2025Multidisciplinary Digital Publishing Institute (MDPI)

Buildings
2025#15Issue 13

The growing demands for sanitary regulations in medical facilities, particularly operating rooms, highlight the importance of ensuring high air quality and minimizing airborne hospital-acquired infections. Improperly designed ventilation systems may lead to contamination of up to 90–95% of patients, especially in light of evolving threats, such as COVID-19. This study focuses on enhancing the energy efficiency and performance of air conditioning and ventilation systems for cleanrooms, where air recirculation is not permissible. A novel energy-efficient direct-flow air treatment scheme is proposed, integrating a heat pump system with adjustable thermal output. A computational fluid dynamics CFD model of a clean operating room was developed to assess the impact of inlet air velocity on aerosol particle removal and airflow stabilization time. The model also considers the effect of personnel movement. The results supported optimized air distribution, reducing microbial contamination risks, with less than 10 CFU/m3, and improved thermal performance. The proposed system was evaluated for energy and cost efficiency compared to conventional setups. Findings can inform the design and operation of cleanroom ventilation in surgical environments and other high-tech applications. This research contributes to improving indoor air quality and reducing infection risks while enhancing sustainability in healthcare infrastructure.

aerosol contaminants , airflow stabilization , cleanroom , computational fluid dynamics (CFD) , operator movement , particle removal efficiency , supply air velocity

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Faculty of General Construction, International Educational Corporation, Ryskulbekova Street, 28, Almaty, 050043, Kazakhstan
Institute of Architecture and Civil Engineering, Satbayev University, Satbayev Street, 22, Almaty, 050013, Kazakhstan
Department of Architecture and Construction Production, Korkyt Ata Kyzylorda University, Aiteke bi Street, 29A, Kyzylorda, 120014, Kazakhstan

Faculty of General Construction
Institute of Architecture and Civil Engineering
Department of Architecture and Construction Production

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